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Nucleic Acid Binding

Nucleic Acid Binding involves temporary non-covalent interaction of a protein or low molecular weight ligand through intermolecular physical forces… Expand
National Institutes of Health

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Highly Cited
2006
Highly Cited
2006
Structural genomics projects as well as ab initio protein structure prediction methods provide structures of proteins with no… Expand
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Highly Cited
2005
Highly Cited
2005
TAR DNA binding protein (TDP43), a highly conserved heterogeneous nuclear ribonucleoprotein, was found to down-regulate splicing… Expand
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Highly Cited
2004
Highly Cited
2004
We describe the solution structures of the Argonaute2 PAZ domain bound to RNA and DNA oligonucleotides. The structures reveal a… Expand
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Highly Cited
2003
Highly Cited
2003
RISC, the RNA-induced silencing complex, uses short interfering RNAs (siRNAs) or micro RNAs (miRNAs) to select its targets in a… Expand
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Review
2000
Review
2000
I am grateful to M. Ares, S. Knight, D. Morse, and E.G.H. Wagner for helpful discussions and apologize to those whose relevant… Expand
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Highly Cited
1999
Highly Cited
1999
The sequence and structural selectivity of 15 different DNA binding agents was explored using a novel, thermodynamically rigorous… Expand
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Review
1995
Review
1995
SELEX is a technology for the identification of high affinity oligonucleotide ligands. Large libraries of random sequence single… Expand
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Highly Cited
1993
Highly Cited
1993
THE cold-shock response in both Escherichia coli and Bacillus subtilis is induced by an abrupt downshift in growth temperature… Expand
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Highly Cited
1990
Highly Cited
1990
The P30 protein of tobacco mosaic virus (TMV) is required for cell to cell movement of viral RNA, which presumably occurs through… Expand
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Highly Cited
1986
Highly Cited
1986
A systematic search for sequences that potentially could form metal-binding domains in proteins has been performed. Five classes… Expand
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