Nuclear speck

Known as: Nuclear speckle, nuclear speckles, splicing speckle 
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Although the cellular interior is crowded with various biological macromolecules, the distribution of these macromolecules is… (More)
Is this relevant?
Highly Cited
2013
Highly Cited
2013
N(6)-methyladenosine (m(6)A) is the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Here we… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2011
Highly Cited
2011
We report here that fat mass and obesity-associated protein (FTO) has efficient oxidative demethylation activity targeting the… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Review
2011
Review
2011
Nuclear bodies including nucleoli, Cajal bodies, nuclear speckles, Polycomb bodies, and paraspeckles are membraneless subnuclear… (More)
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Alternative splicing (AS) of pre-mRNA is utilized by higher eukaryotes to achieve increased transcriptome and proteomic… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2008
Highly Cited
2008
MALAT1 is a long noncoding RNA known to be misregulated in many human cancers. We have identified a highly conserved small RNA of… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Noncoding RNA species play a diverse set of roles in the eukaryotic cell. While much recent attention has focused on smaller RNA… (More)
  • table 1
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Increasing evidence suggests functional compartmentalization of interphase nuclei. This includes preferential interior… (More)
  • figure 5
Is this relevant?
Highly Cited
2000
Highly Cited
2000
DNA replication occurs in microscopically visible complexes at discrete sites (replication foci) in the nucleus. These foci… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1994
Highly Cited
1994
SMALL nuclear ribonucleoprotein particles (snRNPs) and non-snRNP splicing factors containing a serine/arginine-rich domain (SR… (More)
Is this relevant?