FAQ

Nuclear Receptor Subfamily 1, Group D, Member 1

Known as: NR1D1, Nuclear Receptor, Rev-erbA-Alpha, Nuclear Receptors, Rev-erb-alpha 
A DNA-binding orphan nuclear receptor that negatively regulates expression of ARNTL TRANSCRIPTION FACTORS and plays a role as a regulatory component… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1981-2018
051019812018

Related topics

Related topics

36 relations
Biologic DevelopmentCell Differentiation processCell NucleusCell Proliferation
(More)

Narrower (2)

Nr1d1 protein, mouseNr1d1 protein, zebrafish

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Nuclear Receptor Subfamily 1, Group D, Member 1
Cell Differentiation process
Cell Proliferation
physiological aspects
Cell Nucleus
Cytoplasm

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Nuclear Receptor Subfamily 1 Group D Member 1 Regulates Circadian Activity of NLRP3 Inflammasome to Reduce the Severity of Fulminant Hepatitis in Mice.
BACKGROUND & AIMS The innate immune system responds not only to bacterial signals, but also to non-infectious danger-associated… (More)
Is this relevant?
Highly Cited
2014
Highly Cited
2014
Impact of Circadian Nuclear Receptor REV-ERBα on Midbrain Dopamine Production and Mood Regulation
The circadian nature of mood and its dysfunction in affective disorders is well recognized, but the underlying molecular… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2013
Highly Cited
2013
Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription
Rev-Erb-α and Rev-Erb-β are nuclear receptors that regulate the expression of genes involved in the control of circadian rhythm… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 4
Is this relevant?
2007
2007
Transcriptional coactivator PGC-1α integrates the mammalian clock and energy metabolism
The mammalian clock regulates major aspects of energy metabolism, including glucose and lipid homeostasis and mitochondrial… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
The orphan receptor Rev-erbalpha gene is a target of the circadian clock pacemaker.
Rev-erbalpha is a ubiquitously expressed orphan nuclear receptor which functions as a constitutive transcriptional repressor and… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator
As the period length of this pacemaker is only approximately 24 hr, the circadian clock has to be reset every day by an input… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2002
2002
Orphan nuclear hormone receptor Rev-erbalpha regulates the human apolipoprotein CIII promoter.
Apolipoprotein CIII (apoCIII) plays an important role in plasma triglyceride and remnant lipoprotein metabolism. Because… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
1995
1995
Constitutive expression of the orphan receptor, Rev-erbA alpha, inhibits muscle differentiation and abrogates the expression of the myoD gene family.
Rev-erbA alpha is an orphan steroid receptor that is expressed in skeletal muscle. Rev-erbA alpha binds to single/tandem copies… (More)
Is this relevant?
Highly Cited
1989
Highly Cited
1989
Correlation between long-term survival in breast cancer patients and amplification of two putative oncogene-coamplification units: hst-1/int-2 and c-erbB-2/ear-1.
The incidence and association with 10-year survival of amplification in five protooncogenes or transforming genes were… (More)
  • table 1
  • figure I
  • table 2
  • figure 2
  • figure 3
Is this relevant?
1989
1989
Two erbA homologs encoding proteins with different T3 binding capacities are transcribed from opposite DNA strands of the same genetic locus.
Two erbA homologs, termed ear-1 and ear-7, are present in the human genome on chromosome 17. The two genes reside in the same… (More)
Is this relevant?