Noscapine Hydrochloride

Known as: Hydrochloride, Noscapine, Noscapine HCl, 1(3H)Isobenzofuranone,6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3,-dioxolo(4,5-g)isoquinolin-5-yl)-hydrochloride 
The orally available hydrochloride salt of the opioid agonist noscapine, a phthalideisoquinoline alkaloid derived from the opium poppy Papaver… (More)
National Institutes of Health

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1958-2017
0119582017

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Review
2017
Review
2017
  • 2017
Analytical method development and validation are the continuous and inter-dependent task associated with the research and… (More)
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2010
2010
BACKGROUND Noscapine, an alkaloid from Papaver somniferum, widely used as an antitussive, is being clinically studied in the… (More)
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2008
2008
An antitussive plant alkaloid, Noscapine HCl (Nos) displays anticancer activity and has a safe pharmacological profile in humans… (More)
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2003
2003
The cytokinesis block in vitro micronucleus (MN) assay in combination with CREST staining and fluorescence in situ hybridization… (More)
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1999
1999
Noscapine hydrochloride is a centrally acting antitussive opium derivative widely used in cough suppressants. Recent studies have… (More)
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1997
1997
Rapid and accurate binary mixture resolution of chlorpheniramine maleate-noscapine hydrochloride and chlorpheniramine maleate… (More)
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1992
1992
Following exposure to the alkaloid noscapine hydrochloride over a concentration range of 10-120 micrograms/ml immortal cultures… (More)
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1992
1992
The bioavailability of noscapine base administered in lozenges in a dose of 100 mg to twelve healthy volunteers, in a study using… (More)
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1991
1991
Noscapine, a non-narcotic, centrally-acting anti-tussive drug induces polyploidy in Chinese hamster CHL cells; further studies… (More)
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1986
1986
The relative bioavailability and pharmacokinetics of two orally administered aqueous suspensions of noscapine hydrogen embonate… (More)
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