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Noscapine Hydrochloride

Known as: Hydrochloride, Noscapine, Noscapine HCl, 1(3H)Isobenzofuranone,6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3,-dioxolo(4,5-g)isoquinolin-5-yl)-hydrochloride 
The orally available hydrochloride salt of the opioid agonist noscapine, a phthalideisoquinoline alkaloid derived from the opium poppy Papaver… Expand
National Institutes of Health

Papers overview

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2012
2012
The Organization for Economic Co-operation and Development (OECD) has recently adopted Test Guideline 487 (TG487) for conducting… Expand
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2010
2010
BackgroundNoscapine, an alkaloid from Papaver somniferum, widely used as an antitussive, is being clinically studied in the… Expand
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Highly Cited
2008
Highly Cited
2008
PurposeAn antitussive plant alkaloid, Noscapine HCl (Nos) displays anticancer activity and has a safe pharmacological profile in… Expand
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2004
2004
SummaryThe relative bioavailability and pharmacokinetics of two orally administered aqueous suspensions of noscapine hydrogen… Expand
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2003
2003
  • C. Yin, Cui Tang, X. Wu
  • Journal of pharmaceutical and biomedical analysis
  • 2003
  • Corpus ID: 29585938
A high-performance liquid chromatography procedure for the simultaneous determination of aminophylline, methoxyphenamine… Expand
2003
2003
The cytokinesis block in vitro micronucleus (MN) assay in combination with CREST staining and fluorescence in situ hybridization… Expand
1999
1999
Noscapine hydrochloride is a centrally acting antitussive opium derivative widely used in cough suppressants. Recent studies have… Expand
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1997
1997
Rapid and accurate binary mixture resolution of chlorpheniramine maleate-noscapine hydrochloride and chlorpheniramine maleate… Expand
1992
1992
Following exposure to the alkaloid noscapine hydrochloride over a concentration range of 10-120 micrograms/ml immortal cultures… Expand
1991
1991
Noscapine, a non-narcotic, centrally-acting anti-tussive drug induces polyploidy in Chinese hamster CHL cells; further studies… Expand