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Norleucine

Known as: (S)-2-Aminohexanoic Acid, Norleucine [Chemical/Ingredient], Hexanoic Acid, 2-Amino-, (S)- 
An unnatural amino acid that is used experimentally to study protein structure and function. It is structurally similar to METHIONINE, however it… Expand
National Institutes of Health

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18 relations

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2-amino-6-phosphonohexanoic acid6-diazo-5-oxonorleucineBW 175Diazooxonorleucine
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In BloodProcess of secretionagonistsanalogs & derivatives
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Papers overview

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Highly Cited
2011
Highly Cited
2011
Efficacy of Tranexamic Acid in Pediatric Craniosynostosis Surgery: A Double-blind, Placebo-controlled Trial
Background:Extensive blood loss is common in pediatric craniosynostosis reconstruction surgery. Tranexamic acid (TXA) is… Expand
Highly Cited
2009
Highly Cited
2009
Methionine in proteins defends against oxidative stress
A variety of reactive oxygen species react readily with methionine residues in proteins to form methionine sulfoxide, thus… Expand
Highly Cited
2005
Highly Cited
2005
Aβ(31–35) and Aβ(25–35) fragments of amyloid beta‐protein induce cellular death through apoptotic signals: Role of the redox state of methionine‐35
Taken together our result indicate that Aβ(31–35) and Aβ(25–35) peptides in non‐aggregated form, i.e., predominantly monomeric… Expand
Highly Cited
2000
Highly Cited
2000
Vasoactive Intestinal Peptide and Pituitary Adenylyl Cyclase-Activating Polypeptide Inhibit Tumor Necrosis Factor-α Production in Injured Spinal Cord and in Activated Microglia via a cAMP-Dependent…
Tumor necrosis factor-α (TNF-α) production accompanies CNS insults of all kinds. Because the neuropeptide vasoactive intestinal… Expand
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Highly Cited
1994
Highly Cited
1994
Biochemical and pharmacological profile of a potent and selective endothelin B-receptor antagonist, BQ-788.
We describe the characteristics of a potent and selective endothelin (ET) B-receptor antagonist, BQ-788 [N-cis-2,6… Expand
Highly Cited
1989
Highly Cited
1989
Structure of complex of synthetic HIV-1 protease with a substrate-based inhibitor at 2.3 A resolution.
The structure of a complex between a peptide inhibitor with the sequence N-acetyl-Thr-Ile-Nle-psi[CH2-NH]-Nle-Gln-Arg.amide (Nle… Expand
Highly Cited
1985
Highly Cited
1985
Corticotropin-releasing factor receptors are widely distributed within the rat central nervous system: an autoradiographic study
Corticotropin-releasing factor (CRF) receptor-binding sites have been localized and quantified in the rat central nervous system… Expand
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Highly Cited
1977
Highly Cited
1977
Enhancement of nonspecific immunity to Klebsiella pneumoniae infection by a synthetic immunoadjuvant (N-acetylmuramyl-L-alanyl-D-isoglutamine) and several analogs.
N-Acetylmuramyl-L-alanyl-D-isoglutamine and four other synthetic adjuvants that are structural analogs of part of the… Expand
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Highly Cited
1974
Highly Cited
1974
Uptake and metabolism of plasma glutamine by the small intestine.
Abstract An isolated, vascularly perfused preparation of rat intestine extracted large amounts of glutamine (75 µmoles per hour… Expand
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Highly Cited
1960
Highly Cited
1960
Effects of combined drug therapy on metastatic cancer of the testis.
Advanced cancer of the testis was treated in 36 patients with different combinations of an alkylating agent, an antimetabolite… Expand
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