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Nondisjunction, Genetic

Known as: Non-Disjunction, Genetic, Nondisjunctions, Genetic, Genetic Non Disjunction 
The failure of homologous CHROMOSOMES or CHROMATIDS to segregate during MITOSIS or MEIOSIS with the result that one daughter cell has both of a pair… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (1)

Chromosome Aberrations
NONDISJUNCTIONaspects of radiation effectsphysiological aspects

Papers overview

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Highly Cited
1998
Highly Cited
1998
Trichlorfon exposure, spindle aberrations and nondisjunction in mammalian oocytes
Abstract. Consumption of trichlorfon-poisoned fish by women in a small Hungarian village has been associated with trisomy… 
Highly Cited
1994
Highly Cited
1994
The C-terminal domain of Saccharomyces cerevisiae DNA topoisomerase II
A set of carboxy-terminal deletion mutants of Saccharomyces cerevisiae DNA topoisomerase II were constructed for studying the… 
Review
1994
Review
1994
Separation anxiety: the etiology of nondisjunction in flies and people.
Two new studies examine the recombinational history of human chromosomes that nondisjoin at the first meiotic division in females… 
Review
1990
Review
1990
Genetic and epigenetic losses of heterozygosity in cancer predisposition and progression.
Highly Cited
1985
Highly Cited
1985
Cloned DNA probes regionally mapped to human chromosome 21 and their use in determining the origin of nondisjunction.
A number of unique sequence recombinant DNA clones were isolated from a recombinant DNA library constructed from DNA enriched for… 
Highly Cited
1983
Highly Cited
1983
Origin of nondisjunction in trisomy 21 syndrome: all studies compiled, parental age analysis, and international comparisons.
The Q-band polymorphism of chromosome 21 permits assignment of the origin of meiotic nondisjunction by parent and meiotic… 
Highly Cited
1981
Highly Cited
1981
Segregation of recessive phenotypes in somatic cell hybrids: role of mitotic recombination, gene inactivation, and chromosome nondisjunction
Somatic cell hybrids heterozygous at the emetine resistance locus (emtr/emt+) or the chromate resistance locus (chrr/chr+) are… 
Highly Cited
1980
Highly Cited
1980
An experimental approach to the analysis of mechanisms of meiotic nondisjunction and anaphase lagging in primary oocytes.
The in vivo genomic mutagenicity of colchicine in Chinese hamster primary oocytes was analyzed at a carefully chosen dose that… 
Highly Cited
1970
Highly Cited
1970
Meiotic nondisjunction in mice and mouse hybrids.
Nondisjunction in the first meiotic division was evaluated by the frequency of aneuploid metaphase II (M II) figures in secondary… 
Highly Cited
1969
Highly Cited
1969
Studies on chromosomal nondisjunction in man. 3.
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