Non-nucleoside Reverse Transcriptase Inhibitor

Known as: NNRTI 
A substance structurally unlike a nucleoside molecule that is capable of inhibiting the function of a reverse transcriptase. These compounds do not… (More)
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
BACKGROUND The non-nucleoside reverse transcriptase inhibitor (NNRTI), rilpivirine (TMC278; Tibotec Pharmaceuticals, County Cork… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVES The aim of this study was to investigate the frequency of CYP2B6 polymorphisms (according to ethnicity) and the… (More)
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Review
2007
Review
2007
OBJECTIVES Monitoring regional levels of transmitted HIV-1 resistance informs treatment guidelines and provides feedback on the… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE To compare the prevalence of resistance by adherence level in patients treated with non-nucleoside reverse… (More)
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Highly Cited
2004
Highly Cited
2004
Nonnucleoside reverse transcriptase inhibitors (NNRTIs) are potent inhibitors of human immunodeficiency virus type 1 (HIV-1… (More)
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Highly Cited
2004
Highly Cited
2004
Anti-AIDS drug candidate and non-nucleoside reverse transcriptase inhibitor (NNRTI) TMC125-R165335 (etravirine) caused an initial… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVE We have shown that HIV-1 clade C variants contain a valine codon 106 polymorphism (GTG) that facilitates a V106M… (More)
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Highly Cited
2001
Highly Cited
2001
The objectives were to determine the resistance profile and the rate of cross-resistance in HIV-1 infected patients failing an… (More)
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2001
2001
OBJECTIVE To assess the factors associated with virologic response to non-nucleoside reverse transcriptase inhibitor (NNRTI… (More)
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2000
2000
OBJECTIVE To determine the rate of nevirapine resistance in patients failing a nevirapine plus protease inhibitor (PI)-based… (More)
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