Non-Hereditary Clear Cell Renal Cell Carcinoma
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The hypoxia inducible factor (HIF) pathway plays an important role in sporadic clear cell renal cell carcinoma (ccRCC) by… Expand Dear Editor, In a recently published article in Virchows Archiv, Michal et al.  described a very nice and detailed study of… Expand Renal cysts and clear cell renal cell carcinoma are common clinical manifestations of people with germ-line mutations of the von… Expand Aims: Clear cell renal cell carcinoma (CRCC) with diffuse immunoreactivity for CK7 is described. Methods: All cases of CRCC… Expand Loss of von Hippel–Lindau (VHL) tumor suppressor gene function occurs in familial and most sporadic clear cell renal cell… Expand Inactivation of the von Hippel-Lindau tumor suppressor (VHL) is an early event in >60% of sporadic clear cell renal cell… Expand The majority of sporadic clear cell renal cell carcinoma (RCC) is characterized by loss of heterozygosity of the von Hippel… Expand PURPOSE
We determined the primary pathological features of clear cell renal cell carcinoma that are predictive of positive… Expand Background: Overexpression of the hypoxia inducible factor 1 (HIF-1) and HIF-2 transcription factors and the consequent… Expand UNLABELLED
PURPOSE The von Hippel-Lindau (VHL) tumor suppressor gene is frequently inactivated in the common type of sporadic… Expand