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Nocodazole
Known as:
Methyl (5-(2-thienylcarbonyl))-1H-benzimidazol-2-yl
, Carbamic acid, (5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl)-, methyl ester
, Nocodazole [Chemical/Ingredient]
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A synthetic tubulin-binding agent with antineoplastic activity. Nocodazole binds to beta-tubulin and disrupts microtubule assembly/disassembly…
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National Institutes of Health
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Related topics
Related topics
13 relations
Broader (2)
Antineoplastic Agents
Tubulin Modulators
In Blood
Microtubule Process
NCIt Antineoplastic Agent Terminology
agonists
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Narrower (2)
NSC-238159
R-17934
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Modulation of TMEM 16 A channel activity by the von Willebrand factor type A ( VWA ) domain of the calcium-activated chloride channel regulator 1 ( CLCA 1 )
M. Sala-Rabanal
,
Zeynep Yurtsever
,
K. Berry
,
C. Nichols
,
T. Brett
2018
Corpus ID: 3674943
2009
2009
Effects of dimethylsulfoxide (DMSO), nocodazole, and taxol on mast cell histamine secretion.
E. H. Nielsen
,
T. Johansen
Acta Pharmacologica et Toxicologica
2009
Corpus ID: 6652986
Nocodazole depolymerized microtubules and increased the number of microfilaments, and dimethylsulfoxide increased the number of…
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2004
2004
Role of the cytoskeleton in adhesion stabilization of human colorectal carcinoma cells to extracellular matrix components under dynamic conditions of laminar flow
J. Haier
,
G. Nicolson
Clinical and Experimental Metastasis
2004
Corpus ID: 29120165
Adhesion stabilization of malignant cells in the microcirculation is necessary for successful metastasis formation. The adhesion…
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Review
2002
Review
2002
Cytoskeletal Control of Gene Expression : Depolymerization of Microtubules Activates NF-xB
2002
Corpus ID: 11806392
Cell shape changes exert specific effects on gene expression. It has been speculated that the cytoskeleton is responsible for…
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1995
1995
Three-dimensional organization of stable microtubules and the Golgi apparatus in the somata of developing chick sensory neurons
Paul C. Letourneau
,
J. Wire
Journal of Neurocytology
1995
Corpus ID: 25545230
SummaryMicrotubules play a role important in regulating cell shape and in mediating organelle movements. These functions are…
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1992
1992
Induction of colony-stimulating factor receptor expression on hematopoietic progenitor cells: proposed mechanism for growth factor synergism.
S. Jacobsen
,
Francis
,
+5 authors
Keller
Blood
1992
Corpus ID: 33186547
In many cells systems, the cellular interaction between two or more humoral factors leads to a synergistic response in terms of…
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1989
1989
Effect of nocodazole on the water permeability response to vasopressin in rabbit collecting tubules perfused in vitro.
M. Phillips
,
Ann Taylor
Journal of Physiology
1989
Corpus ID: 10987162
1. The effect of the microtubule‐disruptive agent, nocodazole (methyl [5‐(2‐thienylcarbonyl)‐1H‐benzimidazol‐2‐yl] carbamate), on…
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1986
1986
Metabolic inhibitors and mitosis: II. Effects of dinitrophenol/deoxyglucose and nocodazole on the microtubule cytoskeleton
T. Spurck
,
J. Pickett-Heaps
,
M. Klymkowsky
Protoplasma
1986
Corpus ID: 11195494
SummaryTo examine the effects exerted on the microtubule (MT) cytoskeleton by dinitrophenol/deoxyglucose (DNP/DOG) and nocodazole…
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1981
1981
A correlation between in vivo and in vitro effects of the microtubule inhibitors colchicine, parbendazole and nocodazole on myxamoebae of Physarum polycephalum.
R. Quinlan
,
A. Roobol
,
C. I. Pogson
,
K. Gull
Journal of General Microbiology
1981
Corpus ID: 41578188
The effects of the microtubule inhibitors colchicine, parbendazole and nocodazole on the growth of myxamoebae of Physarum…
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1976
1976
[The embryotoxic and antimitotic properties of a series of benzimidazoles].
P. Delatour
,
Y. Richard
The´rapie (Paris)
1976
Corpus ID: 38401847
The binding and inhibitory properties of 11 benzimidazoles for bovine brain tubulin were investigated. The effects of the…
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