Nocodazole

Known as: Methyl (5-(2-thienylcarbonyl))-1H-benzimidazol-2-yl, Carbamic acid, (5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl)-, methyl ester, Nocodazole [Chemical/Ingredient] 
A synthetic tubulin-binding agent with antineoplastic activity. Nocodazole binds to beta-tubulin and disrupts microtubule assembly/disassembly… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
The RhoA GTPase plays a vital role in assembly of contractile actin-myosin filaments (stress fibers) and of associated focal… (More)
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Highly Cited
2004
Highly Cited
2004
The effects of bafilomycin, nocodazole, and reduced temperature on recycling and the lysosomal pathway have been investigated in… (More)
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Highly Cited
2003
Highly Cited
2003
The proper segregation of sister chromatids in mitosis depends on bipolar attachment of all chromosomes to the mitotic spindle… (More)
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Highly Cited
2001
Highly Cited
2001
Simian virus 40 (SV40) is unusual among animal viruses in that it enters cells through caveolae, and the internalized virus… (More)
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Highly Cited
1998
Highly Cited
1998
Bafilomycin A1 (baf), a specific inhibitor of vacuolar proton ATPases, is commonly employed to demonstrate the requirement of low… (More)
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Highly Cited
1998
Highly Cited
1998
During microtubule depolymerization, the central, juxtanuclear Golgi apparatus scatters to multiple peripheral sites. We have… (More)
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Highly Cited
1997
Highly Cited
1997
Previous studies demonstrated that nanomolar concentrations of nocodazole can block cells in mitosis without net microtubule… (More)
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Highly Cited
1995
Highly Cited
1995
The role of microtubules (MTs) in cell locomotion is uncertain: while MTs are not essential for motility of certain cells, MTs… (More)
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Highly Cited
1992
Highly Cited
1992
Inhibition of mitosis by many drugs that bind to tubulin has been attributed to depolymerization of microtubules. However, we… (More)
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Highly Cited
1987
Highly Cited
1987
The subcellular distribution of microtubules containing acetylated alpha-tubulin in mammalian cells in culture was analyzed with… (More)
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