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Nitric Oxide Synthase Inhibitor

Known as: NOS Inhibitor, Nitric Oxide Synthetase Inhibitor 
Any substance that inhibits nitric oxide synthase, an enzyme that catalyzes the production of nitric oxide from L-arginine. Nitric oxide is an… Expand
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
Background—Aerobic exercise enhances endothelium-dependent vasodilation in hypertensive patients, patients with chronic heart… Expand
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Highly Cited
2002
Highly Cited
2002
CONTEXT Increased levels of asymmetric dimethylarginine (ADMA) are associated with endothelial dysfunction and increased risk of… Expand
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Highly Cited
2002
Highly Cited
2002
Background—Recent evidence from cultured endothelial cell studies suggests that phosphorylation of endothelial nitric oxide… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Exposure to risk factors such as hypertension or hypercholesterolemia decreases the bioavailability of endothelium… Expand
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Review
1999
Review
1999
The guanidino-methylated arginine analogue NG monomethyl-L-arginine (L-NMMA) has been the standard nitric oxide synthase… Expand
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Highly Cited
1998
Highly Cited
1998
It has been previously shown that besides synthesizing nitric oxide (NO), neuronal and inducible NO synthase (NOS) generates… Expand
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Essential hypertension is associated with impaired endothelium-dependent vasodilation. Inactivation of endothelium… Expand
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Highly Cited
1997
Highly Cited
1997
  • Y. Xia, J. Zweier
  • Proceedings of the National Academy of Sciences…
  • 1997
  • Corpus ID: 20938221
Superoxide (O-2) and nitric oxide (NO) act to kill invading microbes in phagocytes. In macrophages NO is synthesized by inducible… Expand
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Highly Cited
1994
Highly Cited
1994
Histochemical activity and immunoreactivity of nitric oxide synthase (NOS, EC 1.14.13.39) have been recently demonstrated in… Expand
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Highly Cited
1992
Highly Cited
1992
The direct effects of pro-inflammatory cytokines on the contractility of mammalian heart were studied. Tumor necrosis factor… Expand
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