Nitric Oxide Synthase Inhibitor

Known as: NOS Inhibitor, Nitric Oxide Synthetase Inhibitor 
Any substance that inhibits nitric oxide synthase, an enzyme that catalyzes the production of nitric oxide from L-arginine. Nitric oxide is an… (More)
National Institutes of Health

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Highly Cited
2002
Highly Cited
2002
CONTEXT Increased levels of asymmetric dimethylarginine (ADMA) are associated with endothelial dysfunction and increased risk of… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Exposure to risk factors such as hypertension or hypercholesterolemia decreases the bioavailability of endothelium… (More)
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Highly Cited
1998
Highly Cited
1998
It has been previously shown that besides synthesizing nitric oxide (NO), neuronal and inducible NO synthase (NOS) generates… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Essential hypertension is associated with impaired endothelium-dependent vasodilation. Inactivation of endothelium… (More)
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Highly Cited
1998
Highly Cited
1998
Nitric oxide (NO) plays a role in controlling vascular tone and regulates the contractile properties of cardiac myocytes… (More)
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Highly Cited
1997
Highly Cited
1997
NG,NG-dimethyl-L-arginine (ADMA) is an endogenously synthesized nitric oxide (NO) synthase inhibitor which has potent pressor… (More)
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Highly Cited
1997
Highly Cited
1997
Superoxide (O-2) and nitric oxide (NO) act to kill invading microbes in phagocytes. In macrophages NO is synthesized by inducible… (More)
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Highly Cited
1995
Highly Cited
1995
Nitric oxide (NO) is produced by a variety of cells within the respiratory tract, including inflammatory epithelial cells. NO has… (More)
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Highly Cited
1994
Highly Cited
1994
OBJECTIVE Studies in animals have indicated that increased production of nitric oxide from an inducible isoform of nitric oxide… (More)
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Highly Cited
1992
Highly Cited
1992
The direct effects of pro-inflammatory cytokines on the contractility of mammalian heart were studied. Tumor necrosis factor… (More)
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