Nisoldipine

Known as: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, methyl 2-methylpropyl ester, Nisoldipina, Nisoldipine [Chemical/Ingredient] 
A dihydropyridine calcium channel blocking agent. Nisoldipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Intestinal first-pass metabolism may contribute to low oral drug bioavailability and drug-drug interactions, particularly for… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Although several important studies have been performed in hypertensive type 2 diabetic patients, it is not known… (More)
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Highly Cited
2000
Highly Cited
2000
The L-type alpha(1C) (Ca(v)1.2) calcium channel is the major calcium entry pathway in cardiac and smooth muscle. We inactivated… (More)
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2000
2000
Continuous intravenous infusion of norepinephrine norepinephrine (NE, 0.1 mg/kg/h) induced hypertrophy of the left ventricle (LV… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND It has recently been reported that the use of calcium-channel blockers for hypertension may be associated with an… (More)
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Highly Cited
1998
Highly Cited
1998
1. The regulation of intracellular [Ca2+] in the smooth muscle cells in the wall of small pressurized cerebral arteries (100-200… (More)
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1993
1993
The bioavailability of some dihydropyridine calcium antagonists can be markedly augmented by grapefruit juice and may involve the… (More)
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Highly Cited
1992
Highly Cited
1992
Cellular mechanisms responsible for hypoxic pulmonary vasoconstriction were investigated in pulmonary arterial cells, isolated… (More)
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Highly Cited
1991
Highly Cited
1991
A defined cultivation system was developed for the differentiation of pluripotent embryonic stem cells of the mouse into… (More)
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Highly Cited
1978
Highly Cited
1978
OBJECTIVE The Appropriate Blood Pressure Control in Diabetes (ABCD) Trial is a prospective randomized blinded clinical trial that… (More)
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