Neurotrophic Tyrosine Kinase Receptor Type 1

Known as: Proto-Oncogene Products c-trk, Receptor, NTRK1, p140-trkA 
A protein-tyrosine kinase receptor that is specific for NERVE GROWTH FACTOR; NEUROTROPHIN 3; neurotrophin 4, neurotrophin 5. It plays a crucial role… (More)
National Institutes of Health

Papers overview

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2007
2007
Nerve growth factor (NGF) binds to TrkA receptor and triggers activation of numerous signaling cascades, which play critical… (More)
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Highly Cited
2005
Highly Cited
2005
Retrograde signaling by neurotrophins is crucial for regulating neuronal phenotype and survival. The mechanism responsible for… (More)
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Highly Cited
2003
Highly Cited
2003
The generation of biologically active proteins by regulated intramembrane proteolysis is a highly conserved mechanism in cell… (More)
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Highly Cited
1999
Highly Cited
1999
Nerve growth factor (NGF) is involved in a variety of processes involving signalling, such as cell differentiation and survival… (More)
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Highly Cited
1998
Highly Cited
1998
Null trk1 trk2 mutants of Saccharomyces cerevisiae exhibit a low-affinity uptake of K+ and Rb+. We show that this low-affinity Rb… (More)
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1997
1997
Nerve growth factor (NGF) can influence mast cell development and function in murine rodents by interacting with its receptors on… (More)
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Highly Cited
1997
Highly Cited
1997
It has been hypothesized that the diminished transport of nerve growth factor (NGF) seen within cholinergic basal forebrain (CBF… (More)
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Highly Cited
1996
Highly Cited
1996
We investigated the distribution of the high-affinity neurotrophin receptors TrkA, TrkB, and TrkC in a wide range of normal non… (More)
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Highly Cited
1994
Highly Cited
1994
There is considerable interest in the role of the TRK family of neuotrophin receptors in regulating growth and differentiation in… (More)
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Highly Cited
1991
Highly Cited
1991
NERVE growth factor (NGF) is a neurotrophic factor responsible for the differentiation and survival of sympathetic and sensory… (More)
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