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Research in Alzheimer's disease is focused mainly on younger old persons, whereas studies involving very old persons… Expand OBJECTIVE
To determine the frequency and possible cognitive effect of histological Alzheimer's disease (AD) in autopsied older… Expand The premise of this review is that apolipoprotein (apo) E4 is much more than a contributing factor to neurodegeneration. ApoE has… Expand This review focuses on the potential for traumatic brain injury to evoke both focal and diffuse changes within the brain… Expand Despite general agreement about the boundaries of Alzheimer disease (AD), establishing a maximum limit for Alzheimer-type… Expand Neurodegenerative disorders like Huntington's disease (HD) are characterized by progressive and putative irreversible clinical… Expand The data we report in this study concern the types, location, numbers, forms, and composition of microscopic huntingtin… Expand Our knowledge of the etiology and pathogenesis of Alzheimer's disease is limited. The most conspicuous changes seen in the brain… Expand ALZHEIMER'S disease (AD) is the most common cause of progressive intellectual failure in aged humans. AD brains contain numerous… Expand The Neuropathology Task Force of the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) has developed a practical… Expand