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Neuronal Survival Pathway

Known as: Role of Erk5 in Neuronal Survival 
Axons extend significant distances to innervate target tissues. At the site of innervation, target tissues release neurotrophins including NGF, BDNF… Expand
National Institutes of Health

Related topics

Related topics

29 relations
AKT1 wt AlleleCREB1 protein, humanCREB1 wt AlleleHRAS wt Allele
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Gene expression profile in patients with Gaucher disease indicates activation of inflammatory processes
Gaucher disease (GD) is a rare inherited metabolic disease caused by pathogenic variants in the GBA1 gene. So far, the… Expand
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2019
2019
Tribulusterine Containing Tribulus terrestris Extract Exhibited Neuroprotection Through Attenuating Stress Kinases Mediated Inflammatory Mechanism: In Vitro and In Vivo Studies
The present study has been aimed to explore the different secondary messengers of the inflammatory pathway NF-κB, kinases (JNK… Expand
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2018
2018
PI3K/Akt/GSK3&bgr; induced CREB activation ameliorates arsenic mediated alterations in NMDA receptors and associated signaling in rat hippocampus: Neuroprotective role of curcumin
HIGHLIGHTSProtective role of curcumin in arsenic induced NMDA receptor alterations investigated.Sodium arsenite decreased… Expand
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2014
2014
Silencing of PINK1 Inhibits Insulin-Like Growth Factor-1-Mediated Receptor Activation and Neuronal Survival
The etiology of Parkinson’s disease remains unknown. Mutations in PINK1 have provided an understanding of the molecular… Expand
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2012
2012
Rit GTPase regulates a p38 MAPK-dependent neuronal survival pathway
Rit, along with Rin and Drosophila Ric, comprises the Rit subfamily of Ras-related small GTPases. Although the cellular functions… Expand
2012
2012
Isobaric tagging-based quantification by mass spectrometry of differentially regulated proteins in synaptosomes of HIV/gp120 transgenic mice: Implications for HIV-associated neurodegeneration
HIV/gp120 transgenic mice manifest neuropathological features similar to HIV-associated neurocognitive disorders (HAND) in humans… Expand
Review
2009
Review
2009
Regulation of ceramide-induced neuronal death: Cell metabolism meets neurodegeneration
The present review explores the role of ceramides in neuronal apoptosis, as well as the recent discovery of the signaling… Expand
Review
2005
Review
2005
Nerve Growth Factor-Independent Neuronal Survival: A Role for NO Donors
Because of the limited therapeutic applications of nerve growth factor (NGF), there has been increasing focus on the development… Expand
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Highly Cited
2005
Highly Cited
2005
Essential Role for Sphingosine Kinases in Neural and Vascular Development
ABSTRACT Sphingosine-1-phosphate (S1P), an important sphingolipid metabolite, regulates diverse cellular processes, including… Expand
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Highly Cited
2001
Highly Cited
2001
Selective small‐molecule inhibitors of glycogen synthase kinase‐3 activity protect primary neurones from death
The phosphatidylinositol 3‐kinase (PI 3‐kinase)/protein kinase B (PKB; also known as Akt) signalling pathway is recognized as… Expand
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