Neuronal Survival Pathway
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Gaucher disease (GD) is a rare inherited metabolic disease caused by pathogenic variants in the GBA1 gene. So far, the… Expand The present study has been aimed to explore the different secondary messengers of the inflammatory pathway NF-κB, kinases (JNK… Expand HIGHLIGHTSProtective role of curcumin in arsenic induced NMDA receptor alterations investigated.Sodium arsenite decreased… Expand The etiology of Parkinson’s disease remains unknown. Mutations in PINK1 have provided an understanding of the molecular… Expand Rit, along with Rin and Drosophila Ric, comprises the Rit subfamily of Ras-related small GTPases. Although the cellular functions… Expand HIV/gp120 transgenic mice manifest neuropathological features similar to HIV-associated neurocognitive disorders (HAND) in humans… Expand The present review explores the role of ceramides in neuronal apoptosis, as well as the recent discovery of the signaling… Expand Because of the limited therapeutic applications of nerve growth factor (NGF), there has been increasing focus on the development… Expand ABSTRACT Sphingosine-1-phosphate (S1P), an important sphingolipid metabolite, regulates diverse cellular processes, including… Expand The phosphatidylinositol 3‐kinase (PI 3‐kinase)/protein kinase B (PKB; also known as Akt) signalling pathway is recognized as… Expand