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Neuromedin U

Known as: NMU, NMU-25, Neuromedin U-25 
Expressed throughout the enteric and central nervous systems by human NMU Gene (NMU Family), 174-aa 20-kDa (precursor) secreted Neuromedin U (25-aa… Expand
National Institutes of Health

Related topics

Related topics

7 relations
Intercellular Communication ProcessMuscle ContractionNMU geneTransmembrane Transport
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Broader (1)

Neuropeptides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Neuronal regulation of type 2 innate lymphoid cells via neuromedin U
Group 2 innate lymphoid cells (ILC2s) regulate inflammation, tissue repair and metabolic homeostasis, and are activated by host… Expand
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Highly Cited
2017
Highly Cited
2017
The neuropeptide Neuromedin U stimulates innate lymphoid cells and type 2 inflammation
The type 2 cytokines interleukin (IL)-4, IL-5, IL-9 and IL-13 have important roles in stimulating innate and adaptive immune… Expand
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Highly Cited
2007
Highly Cited
2007
Central control of bone remodeling by neuromedin U
Bone remodeling, the function affected in osteoporosis, the most common of bone diseases, comprises two phases: bone formation by… Expand
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Highly Cited
2005
Highly Cited
2005
Identification of neuromedin S and its possible role in the mammalian circadian oscillator system
The discovery of neuropeptides has resulted in an increased understanding of novel regulatory mechanisms of certain physiological… Expand
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Highly Cited
2004
Highly Cited
2004
Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway
Neuromedin U (NMU) is a hypothalamic neuropeptide that regulates body weight and composition. Here we show that mice lacking the… Expand
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Review
2004
Review
2004
Neuromedin U and Its Receptors: Structure, Function, and Physiological Roles
Neuromedin U (NmU) is a structurally highly conserved neuropeptide. It is ubiquitously distributed, with highest levels found in… Expand
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Highly Cited
2000
Highly Cited
2000
Identification and Characterization of Two Neuromedin U Receptors Differentially Expressed in Peripheral Tissues and the Central Nervous System*
Two structurally related, G-protein-coupled receptors were identified as receptors for the neuropeptide, neuromedin U. This… Expand
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Highly Cited
2000
Highly Cited
2000
Central effects of neuromedin U in the regulation of energy homeostasis.
Neuromedin U (NMU) is a brain-gut peptide whose peripheral activities are well-understood but whose central actions have yet to… Expand
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Highly Cited
2000
Highly Cited
2000
Neuromedin U Is a Potent Agonist at the Orphan G Protein-coupled Receptor FM3*
Neuromedins are a family of peptides best known for their contractile activity on smooth muscle preparations. The biological… Expand
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Highly Cited
2000
Highly Cited
2000
Identification of Neuromedin U as the Cognate Ligand of the Orphan G Protein-coupled Receptor FM-3*
Neuromedin U is a bioactive peptide first isolated from porcine spinal cord. In this paper, we demonstrate that neuromedin U is… Expand
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