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Neotrofin

 
National Institutes of Health

Papers overview

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2013
2013
Depression is one of the most common neuropsychiatric disorders and has been associated with a wide range of neuronal structural… Expand
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2012
2012
Periventricular leukomalacia (PVL) is the dominant form of brain injury in premature infants and no specific treatment is… Expand
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2011
2011
Hypoxia-ischemia is a major cause of perinatal brain injury in the newborn. Neotrofin, a neurotrophin agonist, has been shown to… Expand
2006
2006
We investigated the ability of Neotrofin, an agent that enhances endogenous nerve growth factor (NGF) levels, to prevent… Expand
2003
2003
A phase 1, randomized, double-blind, placebo-controlled, dose escalation study of the purine derivative, AIT-082 (Neotrofin… Expand
2003
2003
There is evidence that heme oxygenase plays a role in cellular defense against reactive oxygen species and thereby has… Expand
2003
2003
We report peripheral actions in rats of Neotrofin, a purine derivative of therapeutic interest. Systemic injections mimicked NGF… Expand
2002
2002
Neotrofin, a reported inducer of CNS neurotrophic factor synthesis and release, with memory-enhancing activity and demonstrated… Expand
2002
2002
PURPOSE Recent research on the purine derivative of hypoxanthine Neotrofin (4-[[3-(1,6-dihydro-6-oxo-9-purin-9-yl)-1-oxopropyl… Expand
2000
2000
A fundamental feature of any drug designed to treat a disease of the central nervous system is the ability to cross the blood… Expand
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