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Nemorubicin Hydrochloride

Known as: 5,12-Naphthacenedione, 7,8,9,10-Tetrahydro-6,8,11-Trihydroxy-8-(Hydroxyacetyl)-1-Methoxy-10-((2,3,6-Trideoxy-3-((2S)-2-Methoxy-4-Morpholinyl)-Alpha-L-Lyxo-Hexopyranosyl)Oxy)-, Hydrochloride, (8S,10S)- 
The hydrochloride salt form of nemorubicin, a morpholinyl analogue of the anthracycline doxorubicin with antineoplastic activity. Nemorubicin is… 
National Institutes of Health

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nemorubicin

Papers overview

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2013
2013
Phase II trial of nemorubicin hydrochloride (N) in combination with cisplatin (cDDP) administered by intra-hepatic artery (IHA) in patients (pts) with hepatocellular carcinoma (HCC): Final results.
e15061 Background: N is a novel DNA-intercalator, mainly metabolized in liver by CYP3A4 enzyme and showing synergic antitumor… 
2008
2008
Nemorubicin hydrochloride (nemorubicin) in combination with cisplatin (cDDP): Phase I in patients (pts) with hepatocellular carcinoma (HCC)
2572 Background: Nemorubicin is a novel DNA-intercalator with: in vivo synergistic antitumor activity with cDDP; a metabolic… 
2007
2007
Phase I study of nemorubicin hydrochloride (nemorubicin), a novel DNA-intercalator, in combination with cisplatin in patients with unresectable hepatocellular carcinoma (HCC)
A139 Background:
 Nemorubicin is a novel DNA-intercalator different from anthracyclines and other anticancer drugs. Its activity… 
2006
2006
Phase I/II trial of nemorubicin hydrochloride in combination with cisplatin is supported by new preclinical evidences of its mechanism of action.
14116 Background: Nemorubicin hydrochloride (nemorubicin) is a non-conventional anthracycline in Phase II evaluation in… 
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