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Nedocromil

Known as: Nedocromilum, 9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano(3,2-g)quinoline-2,8-dicarboxylic acid, 9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano(3,2-g)chinolin-2,8-dicarbonsaeure 
A pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with ASTHMA, including eosinophils, neutrophils… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
BACKGROUND The use of inhaled glucocorticoids for persistent asthma causes a temporary reduction in growth velocity in… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Inhaled corticosteroids (ICS) and long-acting β(2)-agonists (LABAs) are recommended in patients with asthma that is… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Asthma exacerbations, most often caused by respiratory tract infections, are the leading causes of asthma morbidity… Expand
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Highly Cited
2009
Highly Cited
2009
Correlative data suggest that cardiac mast cells are a component of the inflammatory response that is important to hypertension… Expand
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Review
2002
Review
2002
In the treatment of childhood asthma, balancing safety and efficacy is key to achieving optimal therapeutic benefit. Inhaled… Expand
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Review
2001
Review
2001
The authors of this NIH-sponsored study report the long-term effects of 2 inhaled antiinflammatory drugs, budesonide and… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Antiinflammatory therapies, such as inhaled corticosteroids or nedocromil, are recommended for children with asthma… Expand
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Highly Cited
1999
Highly Cited
1999
The Childhood Asthma Management Program (CAMP) is a multicenter, randomized, double-masked clinical trial designed to determine… Expand
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Highly Cited
1994
Highly Cited
1994
Mast cells produce a number of cytokines including IL-6. In view of the large amounts of de novo synthesis induced by the… Expand
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Highly Cited
1978
Highly Cited
1978
Volume 1: immunology biology of eosinophils pathophysiology of allergic inflammation physiology pharmacology principles of… Expand
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