Nedocromil

Known as: Nedocromilum, 9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano(3,2-g)quinoline-2,8-dicarboxylic acid, 9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano(3,2-g)chinolin-2,8-dicarbonsaeure 
A pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with ASTHMA, including eosinophils, neutrophils… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
BACKGROUND The use of inhaled glucocorticoids for persistent asthma causes a temporary reduction in growth velocity in… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Asthma exacerbations, most often caused by respiratory tract infections, are the leading causes of asthma morbidity… (More)
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Highly Cited
2009
Highly Cited
2009
Correlative data suggest that cardiac mast cells are a component of the inflammatory response that is important to hypertension… (More)
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2009
2009
OBJECTIVES To determine whether long-term, continuous use of inhaled anti-inflammatory medications affects asthma outcomes in… (More)
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Highly Cited
2004
Highly Cited
2004
From the Childhood Asthma Management Program cohort, which was randomly assigned to receive budesonide, nedocromil, or placebo… (More)
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2001
2001
The dehydration of nedocromil magnesium (NM) pentahydrate proceeds in two steps, corresponding to the loss of four water… (More)
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1998
1998
Cromolyn and nedocromil are often used in the treatment of asthma. Recently, these agents have been shown to block Cl- currents… (More)
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1995
1995
Elongated, respirable particles of nedocromil were prepared by its crystallization from N-methyl-2-pyrrolidone (NMP) obtained… (More)
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Highly Cited
1994
Highly Cited
1994
Mast cells produce a number of cytokines including IL-6. In view of the large amounts of de novo synthesis induced by the… (More)
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1985
1985
Nedocromil, the disodium salt of a pyranoquinoline dicarboxylic acid, has a similar profile of activity to disodium cromoglycate… (More)
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