Naive T-Lymphocyte

Known as: Naive T Cell, Naive T-Cell, Naive T Lymphocyte 
A mature T-lymphocyte that has differentiated in the bone marrow and undergone central tolerance selection in the thymus but has not interacted with… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1948-2017
0204019482016

Papers overview

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Highly Cited
2007
Highly Cited
2007
Members of the Runx family of transcriptional regulators are required for the appropriate expression of CD4 and CD8 at discrete… (More)
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Highly Cited
2004
Highly Cited
2004
The induction of antigen-specific tolerance in the mature immune system of the intact organism has met with limited success… (More)
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Highly Cited
2003
Highly Cited
2003
CD4+CD25+ regulatory T cells (Treg) are instrumental in the maintenance of immunological tolerance. One critical question is… (More)
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Highly Cited
2000
Highly Cited
2000
In a depleted lymphoid compartment, naive T cells begin a slow proliferation that is independent of cognate antigen yet requires… (More)
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Highly Cited
2000
Highly Cited
2000
The developmental requirements for immunological memory, a central feature of adaptive immune responses, is largely obscure. We… (More)
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Highly Cited
1999
Highly Cited
1999
Allergic asthma, which is present in as many as 10% of individuals in industrialized nations, is characterized by chronic airway… (More)
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Highly Cited
1995
Highly Cited
1995
Fas ligand (FasL) is a membrane-type cytokine belonging to the TNF family, and induces apoptosis through its cell-surface… (More)
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Highly Cited
1995
Highly Cited
1995
CD4+ T helper (Th) cells can be classified into different types based on their cytokine profile. Cells with these polarized… (More)
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Highly Cited
1993
Highly Cited
1993
The effects exerted on the in vitro development of antigen-specific T cell lines and T cell clones by addition or neutralization… (More)
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Highly Cited
1991
Highly Cited
1991
PGE2 is known to inhibit IL-2 and IFN-gamma production from Th cells and is widely viewed as a general immunosuppressant. However… (More)
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