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NXY 059

Known as: NXY-059, NXY059 
 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Background and purpose:  Disodium 2,4‐disulphophenyl‐N‐tert‐butylnitrone (NXY‐059) was neuroprotective in experimental stroke… Expand
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Highly Cited
2008
Highly Cited
2008
Background and Purpose— In animal models of acute ischemic stroke (AIS), the free radical–trapping agent NXY-059 showed promise… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND The free-radical-trapping agent NXY-059 showed promise as a neuroprotectant in the Stroke-Acute Ischemic NXY Treatment… Expand
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Highly Cited
2007
Highly Cited
2007
Background and Purpose— NXY-059 is a free radical-trapping neuroprotectant developed for use in acute ischemic stroke. To… Expand
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Review
2007
Review
2007
  • S. Savitz
  • Experimental Neurology
  • 2007
  • Corpus ID: 32257786
Neuroprotection represents a failed strategy to improve outcome after acute ischemic stroke (AIS). However, most neuroprotective… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND NXY-059 is a free-radical-trapping agent that is neuroprotective in animal models of stroke. We tested whether it… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND AND PURPOSE NXY-059 has substantial protective effects when administered immediately after the onset of ischemia in a… Expand
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Highly Cited
2002
Highly Cited
2002
The efficacy of the free radical trapping agent NXY‐059 in reducing the infarct volume following both transient and permanent… Expand
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Highly Cited
2001
Highly Cited
2001
Background and Purpose— NXY-059 is a novel nitrone with free radical–trapping properties that has a considerable neuroprotective… Expand
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Highly Cited
1999
Highly Cited
1999
Recent results have demonstrated that the spin trapping agent α-phenyl-N-tert-butyl nitrone (PBN) reduces infarct volume in rats… Expand
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