NXY 059

Known as: NXY-059, NXY059 
 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
BACKGROUND AND PURPOSE In animal models of acute ischemic stroke (AIS), the free radical-trapping agent NXY-059 showed promise as… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND The free-radical-trapping agent NXY-059 showed promise as a neuroprotectant in the Stroke-Acute Ischemic NXY Treatment… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND AND PURPOSE NXY-059 is a free radical-trapping neuroprotectant developed for use in acute ischemic stroke. To… (More)
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Review
2007
Review
2007
The SAINT II Trial, a large randomized multicenter clinical trial of the putative neuroprotectant, NXY-059, failed to demonstrate… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND NXY-059 is a free-radical-trapping agent that is neuroprotective in animal models of stroke. We tested whether it… (More)
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Review
2003
Review
2003
Stroke is a major clinical problem, and acute pharmacological intervention with neuroprotective agents has so far been… (More)
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Highly Cited
2002
Highly Cited
2002
1. The efficacy of the free radical trapping agent NXY-059 in reducing the infarct volume following both transient and permanent… (More)
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2001
2001
BACKGROUND AND PURPOSE Increased free radical formation contributes to the damage caused to the brain by acute ischemia. NXY-059… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND AND PURPOSE NXY-059 is a novel nitrone with free radical-trapping properties that has a considerable neuroprotective… (More)
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2001
2001
The nitrones alpha-phenyl-N-tert-butyl nitrone (PBN), sodium 2-sulfophenyl-N-tert-butyl nitrone (S-PBN) and disodium 2,4… (More)
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