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NSC 686288

Known as: NSC-686288 
National Institutes of Health

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aminoflavone

Papers overview

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2014
2014
Abstract 215: Aminoflavone exhibits in vivo efficacy on cancer stem cells in a spontaneous estrogen-dependent breast cancer murine model
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Stem-cell populations have been identified in a range of… 
2014
2014
Abstract 5379: Targeting epidermal growth factor receptor positive breast cancer using nanoparticles loaded with the anti-cancer drug aminoflavone
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Breast cancer is the second leading cause of cancer… 
2010
2010
Abstract 4453: Aryl hydrocarbon receptor activation by Aminoflavone: New molecular target for renal cancer treatment
Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC Aminoflavone (4H-1-benzopyran-4-one, 5-amino-2-(4… 
2009
2009
Validation and implementation of a liquid chromatography/tandem mass spectrometry assay to quantitate aminoflavone (NSC 686288) in human plasma.
2008
2008
Cytokeratin-RNA crosslinking mediated by the antitumor aminoflavone, NSC 686288
3283 Aminoflavone (AF) is an anticancer drug in early clinical trials, and its antiproliferative activity involves the induction… 
2007
2007
Breast cancer cells resistant to anti-hormone treatments retain sensitivity to Aminoflavone (NSC 686288)
PR-4 Aminoflavone (AF; NSC 686288) is a novel anticancer agent which has entered phase I clinical trials. AF has shown exquisite… 
2006
2006
Response of breast cancer cell lines to aminoflavone (NSC 686288) is associated with histone H2AX phosphorylation and estrogen receptor expression
555 Aminoflavone (AF; 5-amino-2,3-fluorophenyl)-6,8-difluoro-7-methyl-4H-1-benzopyran-4-one; NSC 686288) is a novel anticancer… 
2006
2006
CYP1A1 activation of aminoflavone leads to DNA damage in human tumor cell lines
Purpose: Aminoflavone (5-amino-2,3-fluorophenyl)-6,8-difluoro-7-methyl-4H-1-benzopyran-4-one; AF; NSC 686288) is a novel… 
2000
2000
Identification of the principal circulating metabolite of a synthetic 5,4'-diaminoflavone (NSC 686288), an antitumor agent, in the rat.
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