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NSC 181928

Known as: Carbamic acid, (5-amino-1,2-dihydro-3-((methylphenylamino)methyl)pyrido(3,4-b)pyrazin-7-yl)-, ethyl ester, NSC-181298, NSC-181928 
National Institutes of Health

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Broader (1)

Pyrazines

Papers overview

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1995
1995
Inhibition of [3H]mebendazole binding to tubulin by structurally diverse microtubule inhibitors which interact at the colchicine binding site.
A rapid and convenient radioligand assay was used to characterise the interaction of several structurally diverse microtubule… 
1986
1986
Cross-resistance of nocodazole-resistant mutants of CHO cells toward other microtubule inhibitors: similar mode of action of benzimidazole carbamate derivatives and NSC 181928 and TN-16.
Stable mutants which are between 1.6- and 2.2-fold resistant to the microtubule inhibitor, nocodazole (NocR mutants) have been… 
1982
1982
Inhibition of mitosis and anticancer activity against experimental neoplasms by ethyl 5-amino-1,2-dihydro-3-[(N-methylanilino)methyl]-pyrido[3,4-b]pyrazin-7-ylcarbamate (NSC 181928).
Ethyl 5-amino-1,2-dihydro-3-[N-methylanilino)methyl]pyrido[3,4-b]pyrazin-7-ylcarbamate (NSC 181928) is reported to be active… 
1982
1982
Interactions of a new antimitotic agent, NSC-181928, with purified tubulin.
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