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NS 1738

Known as: NS-1738, NS1738 
National Institutes of Health

Papers overview

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2016
2016
Alpha7 nicotinic acetylcholine receptor agonists and PAMs as adjunctive treatment in schizophrenia. An experimental study
Highly Cited
2014
Highly Cited
2014
Presynaptic α7 Nicotinic Acetylcholine Receptors Enhance Hippocampal Mossy Fiber Glutamatergic Transmission via PKA Activation
Nicotinic acetylcholine receptors (nAChRs) are expressed widely in the CNS, and mediate both synaptic and perisynaptic activities… 
Highly Cited
2013
Highly Cited
2013
Effects of alpha 7 positive allosteric modulators in murine inflammatory and chronic neuropathic pain models
Highly Cited
2011
Highly Cited
2011
Competitive binding at a nicotinic receptor transmembrane site of two α7-selective positive allosteric modulators with differing effects on agonist-evoked desensitization
2010
2010
Repeated administration of α7 nicotinic acetylcholine receptor (nAChR) agonists, but not positive allosteric modulators, increases α7 nAChR levels in the brain
J. Neurochem. (2010) 114, 1205–1216. 
Highly Cited
2009
Highly Cited
2009
In Vitro Pharmacological Characterization of a Novel Allosteric Modulator of α7 Neuronal Acetylcholine Receptor, 4-(5-(4-Chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744…
Targeting α7 neuronal acetylcholine receptors (nAChRs) with selective agonists and positive allosteric modulators (PAMs) is… 
2009
2009
Comparative pharmacology and computational modelling yield insights into allosteric modulation of human alpha7 nicotinic acetylcholine receptors.
2009
2009
Characterization of compounds on nicotinic acetylcholine receptor alpha7 channels using higher throughput electrophysiology
Highly Cited
2008
Highly Cited
2008
Positive Allosteric Modulation of the α7 Nicotinic Acetylcholine Receptor: Ligand Interactions with Distinct Binding Sites and Evidence for a Prominent Role of the M2-M3 Segment
The α7 nicotinic acetylcholine receptor (nAChR), a homopentameric, rapidly activating and desensitizing ligand-gated ion channel… 
Highly Cited
2007
Highly Cited
2007
An Allosteric Modulator of the α7 Nicotinic Acetylcholine Receptor Possessing Cognition-Enhancing Properties in Vivo
Augmentation of nicotinic α7 receptor function is considered to be a potential therapeutic strategy aimed at ameliorating… 
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