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NS 1643

Known as: NS-1643, NS1643 
 
National Institutes of Health

Papers overview

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2017
2017
INTRODUCTION The use of multi-electrode arrays (MEA) in combination with human induced pluripotent stem cell-derived… Expand
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2015
2015
Activators of hERG1 such as NS1643 are being developed for congenital/acquired long QT syndrome. Previous studies identify the… Expand
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2013
2013
INTRODUCTION In the present study, we investigated whether a new biomarker - index of cardiac electrophysiological balance (iCEB… Expand
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2013
2013
Traditionally the hERG1 potassium channel has been known to have a fundamental role in membrane excitability of several mammalian… Expand
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2012
2012
Loss-of -function mutations in human ether-a-go-go-related gene 1 (hERG1) is associated with life-threatening arrhythmias. hERG1… Expand
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2010
2010
BACKGROUND AND PURPOSE Kv11.1 channels are involved in regulating cellular excitability in various tissues including brain, heart… Expand
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2008
2008
We studied the mechanisms and sites of activator actions of 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino… Expand
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2008
2008
AIMS Impaired repolarization in cardiac myocytes can lead to long QT syndrome (LQTS), with delayed repolarization and increased… Expand
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Highly Cited
2006
Highly Cited
2006
The cardiac action potential is generated by a concerted action of different ion channels and transporters. Dysfunction of any of… Expand
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Highly Cited
2006
Highly Cited
2006
1,3-Bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643) is a newly discovered activator of human ether-a-go-go-related gene… Expand
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