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NS 11394

Known as: NS-11394, NS11394 
National Institutes of Health

Papers overview

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2018
2018
Probing the molecular basis for affinity/potency‐ and efficacy‐based subtype‐selectivity exhibited by benzodiazepine‐site modulators at GABAA receptors
2016
2016
The α2β3γ2 GABAA receptor preferring agonist NS11394 aggravates dystonia in the phenotypic dtsz model.
2015
2015
GABAA α5 subunit-containing receptors do not contribute to reversal of inflammatory-induced spinal sensitization as indicated by the unique selectivity profile of the GABAA receptor allosteric…
Review
2013
Review
2013
GABA(A) receptor modulation: potential to deliver novel pain medicines?
2012
2012
Assessment of the effects of NS11394 and L-838417, &agr;2/3 subunit-selective GABAA receptor-positive allosteric modulators, in tests for pain, anxiety, memory and motor function
The aim of the present paper was to study the effects of GABAA receptor-positive modulators (L-838417 and NS11394) showing a… 
2012
2012
Positive allosteric modulation of GABA-A receptors reduces capsaicin-induced primary and secondary hypersensitivity in rats
2011
2011
A question of balance – Positive versus negative allosteric modulation of GABAA receptor subtypes as a driver of analgesic efficacy in rat models of inflammatory and neuropathic pain
Highly Cited
2008
Highly Cited
2008
Comparison of the Novel Subtype-Selective GABAA Receptor-Positive Allosteric Modulator NS11394 [3′-[5-(1-Hydroxy-1-methyl-ethyl)-benzoimidazol-1-yl]-biphenyl-2-carbonitrile] with Diazepam, Zolpidem…
Spinal administration of GABAA receptor modulators, such as the benzodiazepine drug diazepam, partially alleviates neuropathic… 
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