NR5A2 protein, human

Known as: Liver Receptor Homolog 1, human liver receptor homologue 1, LRH-1 
Nuclear receptor subfamily 5 group A member 2 (541 aa, ~61 kDa) is encoded by the human NR5A2 gene. This protein is involved in both transcriptional… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Obesity, diabetes, and metabolic syndromes are increasingly recognized as health concerns worldwide. Overnutrition and insulin… (More)
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Highly Cited
2010
Highly Cited
2010
Somatic cells can be reprogrammed to induced pluripotent stem cells (iPSCs) with the introduction of Oct4, Sox2, Klf4, and c-Myc… (More)
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2009
2009
CD8(+) T cells recognizing minor histocompatibility antigens (MiHAs) on leukemic stem and progenitor cells play a pivotal role in… (More)
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Highly Cited
2007
Highly Cited
2007
Bile acids (BAs) are water-soluble end products from cholesterol metabolism and are essential for efficient absorption of dietary… (More)
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2006
2006
The mechanisms responsible for bile acid regulation of mouse intestinal organic solute transporter alpha-beta (Ostalpha-Ostbeta… (More)
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Highly Cited
2005
Highly Cited
2005
The human nuclear receptor liver receptor homolog 1 (hLRH-1) plays an important role in the development of breast carcinomas… (More)
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2005
2005
Cancers, including that of the breast, are the result of multiple contributing factors including aberrant gene expression. Indeed… (More)
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2004
2004
The ATP binding cassette (ABC) half-transporters ABCG5 and ABCG8 facilitate biliary and intestinal removal of neutral sterols… (More)
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Highly Cited
2003
Highly Cited
2003
Adiponectin is a fat-derived hormone with antidiabetic and antiatherogenic properties. Hypoadiponectinemia seen in obesity is… (More)
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Highly Cited
2000
Highly Cited
2000
Bile acids repress the transcription of cytochrome P450 7A1 (CYP7A1), which catalyzes the rate-limiting step in bile acid… (More)
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