NR1I2 protein, human

Known as: Steroid and Xenobiotic Receptor, nuclear receptor subfamily 1, group I, member 2 protein, human, Pregnane X Nuclear Receptor 
Nuclear receptor subfamily 1 group I member 2 (434 aa, ~50 kDa) is encoded by the human NR1I2 gene. This protein is involved in the metabolism of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2017
012320042017

Papers overview

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2017
2017
Lopinavir (LPV), an antiretroviral protease inhibitor frequently prescribed in HIV-positive pregnancies, is a substrate of Abcb1… (More)
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2017
2017
Primary biliary cholangitis (PBC) is an immune-mediated cholestatic liver disease characterized by destruction of the small… (More)
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2014
2014
Cytochrome P450 enzymes, CYP3A and CYP1A are major drug metabolizing enzymes in the liver. CYP3A enzymes have a major role in the… (More)
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2012
2012
Welcome to the June issue of Molecular Endocrinology. The following papers are recommended for your reading. In “The… (More)
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2010
2010
We examined the expression of the steroid and xenobiotic receptor (SXR) and evaluated its clinical significance in human… (More)
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2009
2009
Vitamin K2, known as a cofactor for gamma-carboxylase, also serves as a ligand of a nuclear receptor, Steroid and Xenobiotic… (More)
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2008
2008
BACKGROUND Nuclear receptor subfamily 1, group I, member 2 (NR1I2), commonly known as steroid and xenobiotic receptor (SXR) in… (More)
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2007
2007
INTRODUCTION Steroid and Xenobiotic Receptor (SXR) has demonstrated its activation by numerous drugs, including cytochrome P450… (More)
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2005
2005
ABSTRACTPregnane and Xenobiotic Receptor (PXR; or Steroid and Xenobiotic Receptor, SXR), a new member of the nuclear receptor… (More)
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