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NR1H4 wt Allele

Known as: HRR1, Nuclear Receptor Subfamily 1, Group H, Member 4 wt Allele, FXR 
Human NR1H4 wild-type allele is located in the vicinity of 12q23.1 and is approximately 91 kb in length. This allele, which encodes bile acid… 
National Institutes of Health

Related topics

Related topics

12 relations
12q23.1Biologic DevelopmentCell Differentiation processCell Proliferation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Alisol B 23-acetate promotes liver regeneration in mice after partial hepatectomy via activating farnesoid X receptor.
2013
2013
Abstract 76: MicroRNA-144 Regulates Hepatic ABCA1 and Plasma HDL Following Activation of the Nuclear Receptor FXR
Rationale The bile acid receptor Farnesoid-X-Receptor (FXR) regulates many aspects of lipid metabolism by various complex and not… 
Review
2012
Review
2012
Marine sponge steroids as nuclear receptor ligands.
2012
2012
Synergistic growth inhibition of human hepatocellular carcinoma cells by acyclic retinoid and GW4064, a farnesoid X receptor ligand.
2012
2012
Investigation of imatinib and other approved drugs as starting points for antidiabetic drug discovery with FXR modulating activity.
2011
2011
A formulation-enabled preclinical efficacy assessment of a farnesoid X receptor agonist, GW4064, in hamsters and cynomolgus monkeys.
The farnesoid X receptor (FXR) belongs to one of the human nuclear receptor superfamilies that regulate gene transcription. FXR… 
2008
2008
Pyrazolidine-3,5-dione derivatives as potent non-steroidal agonists of farnesoid X receptor: virtual screening, synthesis, and biological evaluation.
2007
2007
Design, synthesis, and evaluation of non-steroidal farnesoid X receptor (FXR) antagonist.
2006
2006
Diphenylmethane skeleton as a multi-template for nuclear receptor ligands: preparation of FXR and PPAR ligands.
Review
2002
Review
2002
Hepatobiliary transport of bile acids and organic anions.
Recent studies have elucidated the mechanism and regulation of hepatic transport of bile acids and organic anions. Bile acids are… 
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