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NR1H4 gene

Known as: FXR, RETINOID X RECEPTOR-INTERACTING PROTEIN 14, HRR1 
This gene is involved in bile acid binding and metabolism.
National Institutes of Health

Related topics

Related topics

12 relations
Biologic DevelopmentCell Differentiation processCell ProliferationHomeostasis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Farnesoid X receptor, the bile acid sensing nuclear receptor, in liver regeneration
2014
2014
Alisol B 23-acetate promotes liver regeneration in mice after partial hepatectomy via activating farnesoid X receptor.
Highly Cited
2013
Highly Cited
2013
Inhibition of farnesoid X receptor controls esophageal cancer cell growth in vitro and in nude mouse xenografts
Gastroesophageal reflux is a risk factor for esophageal adenocarcinoma, and bile acid and its farnesoid X receptor (FXR) have… 
Review
2012
Review
2012
Marine sponge steroids as nuclear receptor ligands.
2011
2011
Two models of early cardiac rehabilitation in male patients after myocardial infarction with preserved left ventricular function: comparison of standard out-patient versus hybrid training programmes.
BACKGROUND The key to increase the percentage of cardiac patients undergoing cardiac rehabilitation is to follow a well designed… 
Highly Cited
2010
Highly Cited
2010
Retinoic acid represses CYP7A1 expression in human hepatocytes and HepG2 cells by FXR/RXR-dependent and independent mechanisms
Cholesterol 7α-hydroxylase (CYP7A1) plays a key role in maintaining lipid and bile salt homeostasis as it is the rate-limiting… 
2010
2010
Upregulation of scavenger receptor class B type I expression by activation of FXR in hepatocyte.
Highly Cited
2009
Highly Cited
2009
1α,25‐dihydroxyvitamin D3 triggered vitamin D receptor and farnesoid X receptor‐like effects in rat intestine and liver in vivo
1α,25‐Dihydroxyvitamin D3 (1,25(OH)2D3), a natural ligand of the vitamin D receptor (VDR), was found to increase the rat ileal… 
2007
2007
Design, synthesis, and evaluation of non-steroidal farnesoid X receptor (FXR) antagonist.
1983
1983
Bile acid receptors in colorectal cancer
Bile acids are thought to be involved in both the aetiology and development of colorectal cancer. In this study the existence of… 
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