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NR1 protein, human

Known as: NADPH Dependent Diflavin Oxidoreductase 1, NADPH-Dependent FMN and FAD Containing Oxidoreductase, Novel Reductase 1 
NADPH-dependent diflavin oxidoreductase 1 (597 aa, ~67 kDa) is encoded by the human NDOR1 gene. This protein plays a role in the reduction of… Expand
National Institutes of Health

Related topics

Related topics

7 relations
Enzyme GeneNDOR1 geneNDOR1 wt AlleleOxidation-Reduction
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Broader (2)

FlavoproteinsOxidoreductase

Papers overview

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Highly Cited
2010
Highly Cited
2010
Environmental enrichment influences BDNF and NR1 levels in the hippocampus and restores cognitive impairment in chronic cerebral hypoperfused rats.
An enriched environment (EE) is beneficial in modifying behaviors, particularly in tasks involving complex cognitive functions… Expand
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Highly Cited
2008
Highly Cited
2008
Activation of the spinal sigma‐1 receptor enhances NMDA‐induced pain via PKC‐ and PKA‐dependent phosphorylation of the NR1 subunit in mice
Previously we demonstrated that the spinal sigma‐1 receptor (Sig‐1 R) plays an important role in pain transmission, although the… Expand
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Highly Cited
2003
Highly Cited
2003
Expression of NMDA receptor NR1, NR2A and NR2B subunit mRNAs during development of the human hippocampal formation
The N‐methyl‐d‐aspartate receptor plays a critical role in the formation and maintenance of synapses during brain development. In… Expand
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Highly Cited
2002
Highly Cited
2002
Regulation of Calcium/Calmodulin-dependent Protein Kinase II Docking toN-Methyl-d-aspartate Receptors by Calcium/Calmodulin and α-Actinin*
Ca2+ influx through theN-methyl-d-aspartate (NMDA)-type glutamate receptor leads to activation and postsynaptic accumulation of… Expand
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Highly Cited
2001
Highly Cited
2001
An NMDA Receptor ER Retention Signal Regulated by Phosphorylation and Alternative Splicing
Formation of mature excitatory synapses requires the assembly and delivery of NMDA receptors to the neuronal plasma membrane. A… Expand
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Highly Cited
2000
Highly Cited
2000
PDZ Domain Suppression of an ER Retention Signal in NMDA Receptor NR1 Splice Variants
The NMDA receptor NR1 subunit has four splice variants that differ in their C-terminal, cytoplasmic domain. We investigated the… Expand
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Highly Cited
2000
Highly Cited
2000
Ionotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia.
OBJECTIVE Multiple quantifiable biologic abnormalities have been localized to the hippocampus in schizophrenia. Alterations in… Expand
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Highly Cited
1999
Highly Cited
1999
Turnover Analysis of Glutamate Receptors Identifies a Rapidly Degraded Pool of the N-Methyl-d-aspartate Receptor Subunit, NR1, in Cultured Cerebellar Granule Cells*
The number, composition, and location of receptors in neurons are critically important factors in determining the neuron’s… Expand
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Review
1998
Review
1998
Yotiao, a Novel Protein of Neuromuscular Junction and Brain That Interacts with Specific Splice Variants of NMDA Receptor Subunit NR1
The molecular machinery underlying neurotransmitter receptor immobilization at postsynaptic sites is poorly understood. The NMDA… Expand
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Highly Cited
1997
Highly Cited
1997
Differential Surface Expression and Phosphorylation of the N-Methyl-D-aspartate Receptor Subunits NR1 and NR2 in Cultured Hippocampal Neurons*
The trafficking and phosphorylation of the NR1 and NR2 subunits of the N-methyl-D-aspartate-type glutamate receptor complex were… Expand
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