FAQ

NR0B2 wt Allele

Known as: NR0B2, SHP1, SHP 
Human NR0B2 wild-type allele is located in the vicinity of 1p36.1 and is approximately 2 kb in length. This allele, which encodes nuclear receptor… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1983-2017
024619832017

Related topics

Related topics

16 relations
1p36.1Biologic DevelopmentCell Differentiation processCell Proliferation
(More)

Broader (1)

NR0B2 gene

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
NR0B2 wt Allele
Obesity
Cell Differentiation process
Cell Proliferation
Transcriptional Regulation
Homeostasis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
The orphan nuclear receptor SHP acts as a negative regulator in inflammatory signaling triggered by Toll-like receptors
The orphan nuclear receptor SHP (small heterodimer partner) is a transcriptional corepressor that regulates hepatic metabolic… (More)
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Highly Cited
2006
Highly Cited
2006
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
While bile acids (BAs) have long been known to be essential in dietary lipid absorption and cholesterol catabolism, in recent… (More)
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Highly Cited
2005
Highly Cited
2005
Impaired negative feedback suppression of bile acid synthesis in mice lacking betaKlotho.
We have generated a line of mutant mouse that lacks betaKlotho, a protein that structurally resembles Klotho. The synthesis and… (More)
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Highly Cited
2005
Highly Cited
2005
The orphan nuclear receptor SHP regulates PGC-1alpha expression and energy production in brown adipocytes.
Brown adipocytes increase energy production in response to induction of PGC-1alpha, a dominant regulator of energy metabolism. We… (More)
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2003
2003
The small heterodimer partner interacts with the pregnane X receptor and represses its transcriptional activity.
SHP (small heterodimer partner, NR1I0) is an atypical orphan member of the nuclear receptor subfamily in that it lacks a DNA… (More)
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2003
2003
Resistance of SHP-null mice to bile acid-induced liver damage.
The orphan nuclear hormone receptor SHP (gene designation NROB2) is an important component of a negative regulatory cascade by… (More)
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Highly Cited
2002
Highly Cited
2002
The small heterodimer partner interacts with the liver X receptor alpha and represses its transcriptional activity.
The small heterodimer partner SHP (NR0B2) is an unusual nuclear receptor that lacks the typical DNA binding domain common to most… (More)
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Highly Cited
2002
Highly Cited
2002
Dual mechanisms for repression of the monomeric orphan receptor liver receptor homologous protein-1 by the orphan small heterodimer partner.
The orphan nuclear hormone receptor liver receptor homologous protein-1 (LRH-1; NR5A2, also known as FTF), an unusual receptor… (More)
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Highly Cited
2001
Highly Cited
2001
The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp.
BACKGROUND AND AIMS Hepatic bile acid homeostasis is regulated by negative feedback inhibition of genes involved in the uptake… (More)
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Highly Cited
1999
Highly Cited
1999
The orphan nuclear receptor SHP inhibits agonist-dependent transcriptional activity of estrogen receptors ERalpha and ERbeta.
SHP (short heterodimer partner) is an unusual orphan nuclear receptor that contains a putative ligand-binding domain but lacks a… (More)
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