NR0B2 protein, human

Known as: Nuclear Receptor Subfamily 0 Group B Member 2, Orphan Nuclear Receptor SHP, Short Heterodimer Partner 
Nuclear receptor subfamily 0 group B member 2 (257 aa, ~28 kDa) is encoded by the human NR0B2 gene. This protein plays a role in the negative… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2018
0204019842018

Papers overview

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Highly Cited
2006
Highly Cited
2006
While bile acids (BAs) have long been known to be essential in dietary lipid absorption and cholesterol catabolism, in recent… (More)
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Highly Cited
2006
Highly Cited
2006
In Akita and OVE26 mice, two genetic models of type 1 diabetes, diabetic nephropathy is characterized by mesangial expansion and… (More)
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Highly Cited
2004
Highly Cited
2004
We explored the effects of bile acids on triglyceride (TG) homeostasis using a combination of molecular, cellular, and animal… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND AND AIMS The farnesoid X receptor (FXR) is an endogenous sensor for bile acids and inhibits bile acid synthesis by… (More)
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Highly Cited
2002
Highly Cited
2002
The orphan nuclear hormone receptor SHP has been proposed to have a key role in the negative feedback regulation of bile acid… (More)
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Highly Cited
2002
Highly Cited
2002
The in vivo role of the nuclear receptor SHP in feedback regulation of bile acid synthesis was examined. Loss of SHP in mice… (More)
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Highly Cited
2000
Highly Cited
2000
The catabolism of cholesterol into bile acids is regulated by oxysterols and bile acids, which induce or repress transcription of… (More)
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Highly Cited
2000
Highly Cited
2000
Bile acids repress the transcription of cytochrome P450 7A1 (CYP7A1), which catalyzes the rate-limiting step in bile acid… (More)
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Highly Cited
1996
Highly Cited
1996
SHP is an orphan member of the nuclear hormone receptor superfamily that contains the dimerization and ligand-binding domain… (More)
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Highly Cited
1995
Highly Cited
1995
CD22 is a membrane immunoglobulin (mIg)-associated protein of B cells. CD22 is tyrosine-phosphorylated when mIg is ligated… (More)
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