NPS2143

Known as: NPS 2143 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2008-2018
02420082018

Papers overview

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2017
2017
NPS 2143, a novel and selective antagonist of calcium-sensing receptor (CaSR) has been reported to possess anti-inflammatory… (More)
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2016
2016
Mucus overproduction is a fundamental hallmark of COPD that is caused by exposure to cigarette smoke. MUC5AC is one of the main… (More)
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2014
2014
Elevated extracellular calcium has been shown to promote the differentiation of osteoblasts. However, the way that calcium… (More)
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2013
2013
The "amyloid-β (Aβ) hypothesis" posits that accumulating Aβ peptides (Aβs) produced by neurons cause Alzheimer's disease (AD… (More)
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2013
2013
CCK is secreted by endocrine cells of the proximal intestine in response to dietary components, including amino acids. CCK plays… (More)
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2013
2013
(R)-3 (NPS 2143) is a negative allosteric modulator of the human calcium-sensing receptor (CaSR) and as such represents an… (More)
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2012
2012
Recently, we reported that calcium-sensing receptor (CaSR) is a receptor for kokumi substances, which enhance the intensities of… (More)
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2010
2010
As a G protein-coupled receptor, the extracellular Ca(2+)-sensing receptor (CaSR) responds to changes not only in extracellular… (More)
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2010
2010
Calcilytics, antagonists of calcium receptor, decrease sensitivity of this receptor to plasma calcium concentration and increase… (More)
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2008
2008
Intraluminal L-phenylalanine (Phe) stimulates cholecystokinin (CCK) secretion in vivo and in vitro. However, the cellular… (More)
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