NOTCH4 protein, human

Known as: neurogenic locus notch homolog protein 4, human, hNotch4, Notch homolog 4 (Drosophila) protein, human 
Neurogenic locus notch homolog protein 4 (2003 aa, ~210 kDa) is encoded by the human NOTCH4 gene. This protein plays a role in both cell-fate… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
0519972017

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2015
2015
Breast cancers (BCs) typically express estrogen receptors (ERs) but frequently exhibit de novo or acquired resistance to hormonal… (More)
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2012
2012
We have performed a meta-analysis of the major-histocompatibility-complex (MHC) region in systemic lupus erythematosus (SLE) to… (More)
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2009
2009
Transgenic mice expressing the Notch 4 intracellular domain (ICD) (Int3) in the mammary gland have two phenotypes: arrest of… (More)
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2009
2009
Increased expression of Notch signaling pathway components is observed in Kaposi sarcoma (KS) but the mechanism underlying the… (More)
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Highly Cited
2005
Highly Cited
2005
Genomes of solid tumors are characterized by gains and losses of regions, which may contribute to tumorigenesis by altering gene… (More)
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2005
2005
The process whereby the primitive vascular network develops into the mature vasculature, known as angiogenic vascular remodeling… (More)
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2005
2005
A considerable proportion of heritable human phenotypic variation is thought to result from altered gene expression… (More)
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2004
Highly Cited
2004
The mammalian F-box protein Fbw7 and its Caenorhabditis elegans counterpart Sel-10 have been implicated in the ubiquitin-mediated… (More)
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2000
2000
Linkage disequilibrium mapping of the MHC region in 80 British parent-offspring trios showed that NOTCH4 was highly associated… (More)
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2000
2000
Notch receptors are involved in regulating the balance between cell differentiation and stem cell proliferation during the… (More)
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