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NMNAT2 gene

Known as: PYRIDINE NUCLEOTIDE ADENYLYLTRANSFERASE 2, KIAA0479, PNAT2 
 
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Nicotinamide mononucleotide adenylyl transferase 2 (NMNAT2) is neuroprotective in numerous preclinical models of… Expand
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Highly Cited
2015
Highly Cited
2015
Summary SARM1 function and nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) loss both promote axon degeneration, but… Expand
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Highly Cited
2013
Highly Cited
2013
NMNAT2 is an NAD+-synthesizing enzyme with an essential axon maintenance role in primary culture neurons. We have generated an… Expand
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Highly Cited
2013
Highly Cited
2013
Modulation of the subcellular localization of the endogenous axon survival factor Nmnat2 boosts its axon protective capacity… Expand
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2013
2013
Lung cancer is the leading cause of death worldwide and associated with dismal prognoses. As a major mitochondrial deacetylase… Expand
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Highly Cited
2012
Highly Cited
2012
Tauopathies, characterized by neurofibrillary tangles (NFTs) of phosphorylated tau proteins, are a group of neurodegenerative… Expand
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2012
2012
Using transposon-mediated gene-trap mutagenesis, we have generated a novel mouse mutant termed Blad (Bloated Bladder). Homozygous… Expand
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Highly Cited
2012
Highly Cited
2012
The discovery of sirtuins (SIRT), a family of nicotinamide adenine dinucleotide (NAD)‐dependent deacetylases, has indicated that… Expand
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Highly Cited
2010
Highly Cited
2010
We conclude that endogenous Nmnat2 prevents spontaneous degeneration of healthy axons and propose that, when present, the more… Expand
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2010
2010
Nicotinamide mononucleotide (NMN) adenylyltransferase 2 (Nmnat2) catalyzes the synthesis of NAD from NMN and ATP. The Nmnat2… Expand
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