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NLRC4 gene

Known as: NLRC4, CLANA, CLANB 
 
National Institutes of Health

Papers overview

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Review
2019
Review
2019
ABSTRACT Mitophagy is a vital form of autophagy for selective removal of dysfunctional or redundant mitochondria. Accumulating… Expand
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Review
2018
Review
2018
15 years ago, the fundamental biology of an inflammatory signaling complex eventually dubbed “the inflammasome” began to unravel… Expand
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Review
2017
Review
2017
Inflammasomes are protein complexes formed upon encounter of microbial or damage-associated stimuli. The main output of… Expand
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Highly Cited
2015
Highly Cited
2015
The NOD-like receptor (NLR) family, pyrin domain–containing protein 3 (NLRP3) inflammasome is a component of the inflammatory… Expand
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Review
2009
Review
2009
The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes secretion of the… Expand
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Highly Cited
2007
Highly Cited
2007
Inflammasomes are Nod-like receptor(NLR)- and caspase-1-containing cytoplasmic multiprotein complexes, which upon their assembly… Expand
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Highly Cited
2006
Highly Cited
2006
Gram-negative bacteria that replicate in the cytosol of mammalian macrophages can activate a signaling pathway leading to caspase… Expand
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Highly Cited
2006
Highly Cited
2006
Macrophages respond to Salmonella typhimurium infection via Ipaf, a NACHT–leucine-rich repeat family member that activates… Expand
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Highly Cited
2004
Highly Cited
2004
Specific adaptors regulate the activation of initiator caspases; for example, FADD and Apaf-1 engage caspases 8 and 9… Expand
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Highly Cited
1995
Highly Cited
1995
Homeostasis can be defined as the tendency of a cell or an organism to maintain internal steady state, even in response to any… Expand
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