NIMA-Related Kinases

Known as: NEK Family Kinases, NEK Kinases, Kinases, Never-in-Mitosis A 
A highly-conserved family of protein serine-threonine kinases that regulate the CELL CYCLE; MITOSIS; and the response to DNA DAMAGE. They are also… (More)
National Institutes of Health

Papers overview

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Review
2013
Review
2013
The correct assembly and timely disassembly of the mitotic spindle is crucial for the propagation of the genome during cell… (More)
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Highly Cited
2009
Highly Cited
2009
The Janus kinases (JAKs) are a pivotal family of protein tyrosine kinases (PTKs) that play prominent roles in numerous cytokine… (More)
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Review
2007
Review
2007
The NIMA-related kinases represent a family of serine/threonine kinases implicated in cell cycle control. The founding member of… (More)
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Review
2005
Review
2005
The Nek family of cell-cycle kinases is widely represented in eukaryotes and includes numerous proteins that were described only… (More)
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Highly Cited
2004
Highly Cited
2004
The Abl kinase inhibitor imatinib mesylate is the preferred treatment for Philadelphia chromosome–positive (Ph+) chronic myeloid… (More)
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Highly Cited
2003
Highly Cited
2003
c-Abl is normally regulated by an autoinhibitory mechanism, the disruption of which leads to chronic myelogenous leukemia. The… (More)
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Highly Cited
2003
Highly Cited
2003
Tousled-like kinases (TLKs) constitute a family of serine/threonine kinases conserved in plants and animals that act in a cell… (More)
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Highly Cited
2002
Highly Cited
2002
Phosphorylation at a highly conserved serine residue (Ser-10) in the histone H3 tail is considered to be a crucial event for the… (More)
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Highly Cited
1999
Highly Cited
1999
Tyrosine phosphorylation of focal adhesion kinase (FAK) creates a high-affinity binding site for the src homology 2 domain of the… (More)
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Highly Cited
1995
Highly Cited
1995
The induction of gene transcription in response to gamma interferon is impaired in mononuclear phagocytes infected with… (More)
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