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NID2 protein, human

Known as: Nidogen-2, nidogen-2 protein, human, nidogen 2 protein, human 
Nidogen-2 (1375 aa, ~151 kDa) is encoded by the human NID2 gene. This protein plays a role in both basement membrane structure and cell adhesion.
National Institutes of Health

Related topics

Related topics

14 relations
Basement membraneCell AdhesionCell MovementCell-Matrix Junction
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Broader (1)

Cell Adhesion Molecules

Papers overview

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2014
2014
Extracellular matrix remodeling by bone marrow fibroblast-like cells correlates with disease progression in multiple myeloma.
The pathogenesis of multiple myeloma (MM) is regarded as a multistep process, in which an asymptomatic stage of monoclonal… Expand
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Highly Cited
2007
Highly Cited
2007
Compositional differences between infant and adult human corneal basement membranes.
PURPOSE Adult human corneal epithelial basement membrane (EBM) and Descemet's membrane (DM) components exhibit heterogeneous… Expand
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Highly Cited
2007
Highly Cited
2007
A comparative analysis of the fibulin protein family. Biochemical characterization, binding interactions, and tissue localization.
Fibulins are a family of five extracellular matrix proteins characterized by tandem arrays of epidermal growth factor-like… Expand
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Highly Cited
2006
Highly Cited
2006
Venular basement membranes contain specific matrix protein low expression regions that act as exit points for emigrating neutrophils
The mechanism of leukocyte migration through venular walls in vivo is largely unknown. By using immunofluorescence staining and… Expand
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2002
2002
The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin.
Type XIII collagen consists of a short N-terminal intracellular domain, a transmembrane domain, and a collagenous ectodomain, and… Expand
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2001
2001
Mapping of binding sites for nidogens, fibulin-2, fibronectin and heparin to different IG modules of perlecan.
Perlecan, a major basement membrane proteoglycan, has a complex modular structure designed for the binding of many cellular and… Expand
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Highly Cited
1999
Highly Cited
1999
Angiogenesis inhibitor endostatin is a distinct component of elastic fibers in vessel walls.
Theendothelial cell inhibitor endostatin (22 kDa) is part of the carboxyl-terminal globular domain of collagen XVIII and shows a… Expand
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Highly Cited
1999
Highly Cited
1999
Binding of the G domains of laminin alpha1 and alpha2 chains and perlecan to heparin, sulfatides, alpha-dystroglycan and several extracellular matrix proteins.
The C-terminal G domain of the mouse laminin alpha2 chain consists of five lamin-type G domain (LG) modules (alpha2LG1 to… Expand
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Highly Cited
1999
Highly Cited
1999
Recombinant domain IV of perlecan binds to nidogens, laminin-nidogen complex, fibronectin, fibulin-2 and heparin.
Domain IV of mouse perlecan, which consists of 14 immunoglobulin superfamily (IG) modules, was prepared from recombinant human… Expand
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Highly Cited
1998
Highly Cited
1998
Nidogen-2: a new basement membrane protein with diverse binding properties.
Human nidogen-2 was cloned and sequenced (1375 residues) and found to share 46% sequence identity and a similar domain… Expand
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