NF 279

RATIONALE The role of purinergic signaling in human ENS is not well understood. We sought to further characterize the… Expand

BACKGROUND AND PURPOSE Ionotropic purinoreceptors (P2X) in renal vascular smooth muscle cells (RVSMCs) are involved in mediating… Expand

BACKGROUND AND PURPOSE Acute activation of P2X7 receptors rapidly opens a non-selective cation channel. Sustained P2X7 receptor… Expand

Acetylcholine and ATP are excitatory cotransmitters in parasympathetic nerves. We used P2X1 receptor antagonists to further… Expand

The aim of this study was to characterise the P2 receptors involved in purinergic relaxant responses in rat distal colon circular… Expand

The functional significance of extracellular signal-regulated kinase 2 (ERK2) activation was investigated during shear induced… Expand

ATP-gated P2X1 receptors feature fast activation and fast desensitization combined with slow recovery from desensitized states… Expand

This study tests the hypothesis that P2X1 receptors mediate pressure-induced afferent arteriolar autoregulatory responses… Expand

Fast P2X receptor-mediated excitatory postsynaptic current (EPSC) was identified in pyramidal neurones of layer II/III of somato… Expand

The present study employed standard peroxidase immunohistochemistry to map the distribution of P2Y(1) receptors in the rat… Expand