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NF 279

Known as: NF-279, NF279 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Purinergic AntagonistsSuramin
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Mammalian P2X7 receptor pharmacology: comparison of recombinant mouse, rat and human P2X7 receptors
Background and purpose:  Acute activation of P2X7 receptors rapidly opens a non‐selective cation channel. Sustained P2X7 receptor… 
Highly Cited
2007
Highly Cited
2007
Inhibitory purinergic P2 receptor characterisation in rat distal colon
Highly Cited
2007
Highly Cited
2007
Identification of Atropine- and P2X1 Receptor Antagonist-Resistant, Neurogenic Contractions of the Urinary Bladder
Acetylcholine and ATP are excitatory cotransmitters in parasympathetic nerves. We used P2X1 receptor antagonists to further… 
Highly Cited
2004
Highly Cited
2004
Desensitization Masks Nanomolar Potency of ATP for the P2X1 Receptor*
ATP-gated P2X1 receptors feature fast activation and fast desensitization combined with slow recovery from desensitized states… 
Highly Cited
2003
Highly Cited
2003
Physiological role for P2X1 receptors in renal microvascular autoregulatory behavior.
This study tests the hypothesis that P2X1 receptors mediate pressure-induced afferent arteriolar autoregulatory responses… 
Highly Cited
2003
Highly Cited
2003
Physiological role for P2X1 receptors in renal microvascular autoregulatory behavior
This study tests the hypothesis that P2X1 receptors mediate pressure-induced afferent arteriolar autoregulatory responses… 
Highly Cited
2002
Highly Cited
2002
Ionotropic P2X purinoreceptors mediate synaptic transmission in rat pyramidal neurones of layer II/III of somato‐sensory cortex
Fast P2X receptor‐mediated excitatory postsynaptic current (EPSC) was identified in pyramidal neurones of layer II/III of somato… 
2002
2002
Immunoreactive localisation of P2Y1 receptors within the rat and human nodose ganglia and rat brainstem: comparison with [α33P]deoxyadenosine 5′-triphosphate autoradiography
Highly Cited
2000
Highly Cited
2000
The suramin analogue NF279 is a novel and potent antagonist selective for the P2X1 receptor
Highly Cited
1998
Highly Cited
1998
NF279: a novel potent and selective antagonist of P2X receptor-mediated responses.
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