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NEK2 gene

Known as: NEVER IN MITOSIS GENE A-RELATED KINASE 2, PPP1R111, protein phosphatase 1, regulatory subunit 111 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
MiR-486-5p negatively regulates oncogenic NEK2 in hepatocellular carcinoma
NEK2 is a member of the NIMA-related family of serine/threonine centrosomal kinases. We analyzed the relationship between… 
2017
2017
MiR-486-5p negatively regulates oncogenic NEK2 in hepatocellular carcinoma.
NEK2 is a member of the NIMA-related family of serine/threonine centrosomal kinases. We analyzed the relationship between… 
2017
2017
Overexpression of NIMA-related kinase 2 is associated with poor prognoses in malignant glioma
Eleated expression of NIMA-related kinase 2 (NEK2) was frequently observed in a variety of malignant cancers, and it appears to… 
2016
2016
Nek2A/SuFu feedback loop regulates Gli-mediated Hedgehog signaling pathway
Suppressor of Fused (SuFu), one of the most conserved components of the Hedgehog (Hh) signaling, binds Gli transcription factors… 
2013
2013
NEK 2 Induces Drug Resistance Mainly through Activation of Efflux Drug Pumps and Is Associated with Poor Prognosis in Myeloma and Other Cancers
Wen Zhou,1,3,6 Ye Yang,1,3,6 Jiliang Xia,1,3,6 He Wang,1,3,6 Mohamed E. Salama,2 Wei Xiong,3 Hongwei Xu,1,3 Shashirekha Shetty,4… 
2013
2013
Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A) Protein Is Involved in Centrosome Separation through the Regulation of NIMA (Never In Mitosis Gene A)-related Kinase 2 (NEK2) Protein Activity*
Background: Cancerous inhibitor of protein phosphatase 2A (CIP2A) is overexpressed in most types of human cancer. Results… 
2011
2011
Possible involvement of Nemo-like kinase 1 in Xenopus oocyte maturation as a kinase responsible for Pumilio1, Pumilio2, and CPEB phosphorylation.
Members of the mitogen-activated protein kinase (MAPK) family play important roles in Xenopus oocyte maturation. Nemo-like kinase… 
Review
2010
Review
2010
Cyclin A and Nek2A: APC/C-Cdc20 substrates invisible to the mitotic spindle checkpoint.
Active cyclin B1-Cdk1 (cyclin-dependent kinase 1) keeps cells in mitosis, allowing time for spindle microtubules to capture the… 
2005
2005
Live cell imaging reveals distinct roles in cell cycle regulation for Nek2A and Nek2B.
2004
2004
The Centrosomal Kinase Nek 2 Displays Elevated Levels of Protein Expression in Human Breast Cancer
Aneuploidy and chromosome instability are common abnormalities in human cancer. Loss of control over mitotic progression… 
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