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NADPH oxidase activity

Known as: NAD(P)H oxidase activity, NAD(P)H:oxygen oxidoreductase activity, NADPH oxidase 
Catalysis of the reaction: NAD(P)H + H+ + O2 = NAD(P)+ + hydrogen peroxide. [EC:1.6.3.1]
National Institutes of Health

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3 relations
NADPH Oxidasenegative regulation of NAD(P)H oxidase activityp138tox

Papers overview

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2020
2020
ATR-IR and EPR spectroscopy for following the membrane restoration of isolated cortical synaptosomes in aluminium-induced Alzheimer's disease - Like rat model.
2015
2015
Regulation of blood pressure, oxidative stress and AT1R by high salt diet in mutant human dopamine D5 receptor transgenic mice
Humans have dopamine D5 receptors (hD5R) with single-nucleotide polymorphisms and a diminished function. We generated hD5F173L… 
2003
2003
Long-term high-level reconstitution of NADPH oxidase activity in murine X-linked chronic granulomatous disease using a bicistronic vector expressing gp91phox and a Delta LNGFR cell surface marker.
A murine model of X-linked chronic granulomatous disease (X-CGD), an inherited immune deficiency with absent phagocyte NADPH… 
2003
2003
The antiangiogenic agent SU5416 down-regulates phorbol ester-mediated induction of cyclooxygenase 2 expression by inhibiting nicotinamide adenine dinucleotide phosphate oxidase activity.
Increased expression of cyclooxygenase (COX) 2 and the production of PGs appear to provide a survival advantage to transformed… 
1998
1998
NADPH oxidase activity and cytochrome b558 content of human Epstein-Barr-virus-transformed B lymphocytes correlate with expression of genes encoding components of the oxidase system.
We investigated the NADPH oxidase activity, cytochrome b558 content, and gene expression of gp91-phox and p47-phox in normal… 
1998
1998
Reconstitution of NADPH oxidase activity in human X-linked chronic granulomatous disease myeloid cells after stable gene transfer using a recombinant adeno-associated virus 2 vector.
X-linked chronic granulomatous disease (X-CGD) is an inherited disorder of host defense that results from mutations in the gene… 
Highly Cited
1996
Highly Cited
1996
Phorbol myristate acetate‐induced NADPH oxidase activity in human neutrophils: only half the story has been told
The paradigm for activation of the neutrophil NADPH oxidase with the protein kinase C activator phorbol myristate acetate (PMA… 
1990
1990
Involvement of membrane charges in constituting the active form of NADPH oxidase in guinea pig polymorphonuclear leukocytes.
1977
1977
A comparison between the NADPH oxidase activity of human polymorphonuclear leukocytes and the oxidase activity of several purified peroxidases.
1976
1976
Studies on the mechanism of metabolic stimulation in polymorphonuclear leukocytes during phagocytosis. Activators and inhibitors of the granule bound NADPH oxidase
SummaryThe effects of several known inhibitors and activators of peroxidase-catalyzed reactions have been studied on the NADPH… 
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