NAD+ ADP-ribosyltransferase activity

Known as: NAD ADP-ribosyltransferase activity, poly(ADP-ribose) synthetase activity, poly(ADP-ribose)polymerase activity 
Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor. [EC:2.4.2.30]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2017
024619772017

Papers overview

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2014
2014
Rheumatoid arthritis (RA) is a disease that is still insufficiently controlled by current treatments. Poly(ADP-ribose) polymerase… (More)
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2003
2003
Apoptosis plays a pivotal role in development, tissue homeostasis, cancer, immune defense, and response to weightlessness. It can… (More)
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1998
1998
The nuclear enzyme poly(ADP-ribose) synthetase (PARS) is activated by DNA strand breakage, caused, for example by nitric oxide… (More)
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1998
1998
Poly (ADP-ribose) polymerase (PARP), a nuclear enzyme responsible for DNA strand breaks, has been recently suggested to be… (More)
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1996
1996
Injury and inflammation lead to hypoxia and elevated lactate in wounds. This redox environment establishes cells in a reparative… (More)
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1990
1990
Ewing's sarcoma (ES) is a highly malignant childhood bone tumor and is considered curable by moderate doses of radiotherapy. The… (More)
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1982
1982
Treatment of Ehrlich ascites tumor cells with the trifunctional alkylating agent 2,3-5-tris(ethyleneimino)benzoquinone-1,4… (More)
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1981
1981
Differentiation of 3T3-L1 preadipocytes, induced by methylisobutylxanthine (MIX), dexamethasone (DEX), and insulin, produces… (More)
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1979
1979
Poly(adenosine diphosphate ribose) polymerase, a chromatin-bound enzyme, was stimulated 150 to 200% after treatment of HeLa cells… (More)
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1977
1977
The distribution of a chromatin-bound, nuclear protein modifying enzyme, poly (adenosine diphosphate-ribose) polymerase, and its… (More)
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