N-sulfoglucosamine sulfohydrolase activity

Known as: N-sulfo-D-glucosamine sulfohydrolase activity, N-sulphoglucosamine sulphohydrolase activity, heparin sulfamidase activity 
Catalysis of the reaction: N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate. [EC:3.10.1.1]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1974-2015
01219742015

Papers overview

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2015
2015
Deficient N-sulfoglucosamine sulfohydrolase (SGSH) enzyme activity causes mucopolysaccharidosis (MPS) type IIIA. A fluorimetric… (More)
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2014
2014
Heparan sulfate (HS) catabolism begins with endo-degradation of the polysaccharide to smaller HS oligosaccharides, followed by… (More)
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2008
2008
Mucopolysaccharidosis type IIIA (MPS IIIA) is a heritable glycosaminoglycan (GAG) storage disorder which is characterised by… (More)
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2003
2003
Sanfilippo A syndrome, mucopolysaccharidosis type IIIA, is caused by a deficiency of heparan sulphamidase activity, and usually… (More)
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1999
1999
Mucopolysaccharidosis type IIIA (SanÐlippo A; McKusick 25290) is caused by a deÐciency of lysosomal sulphamidase activity (EC 3… (More)
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1996
1996
4-Methylumbelliferyl-α-d-N-sulphoglucosaminide (MU-α-GlcNS) was synthesized and shown to be a substrate for the lysosomal heparin… (More)
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1993
1993
Early amniocentesis performed at 13 weeks gestation was utilized to obtain amniocytes for culture. Sonicates of cultured… (More)
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1986
1986
Human sulphamate sulphohydrolase was purified at least 20,000-fold to homogeneity from liver with a three-step four-column… (More)
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1981
1981
1. Sulphamidase activity was assayed by incubation of the radiolabelled disaccharide O-(alpha-2-sulphamino-2-deoxy-D… (More)
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1974
1974
A sulphamidase activity present in rat spleen capable of hydrolysing N-[(35)S]sulphated heparin was studied. This activity was… (More)
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