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N-sulfoglucosamine sulfohydrolase activity

Known as: N-sulfo-D-glucosamine sulfohydrolase activity, N-sulphoglucosamine sulphohydrolase activity, heparin sulfamidase activity 
Catalysis of the reaction: N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate. [EC:3.10.1.1]
National Institutes of Health

Papers overview

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2019
2019
Mucopolysaccharidosis (MPS) IIIA, also known as Sanfilippo syndrome type A, is a severe, progressive disease that affects the… Expand
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Highly Cited
2013
Highly Cited
2013
Mucopolysaccharidoses type IIIA (MPS‐IIIA) is a neurodegenerative lysosomal storage disorder (LSD) caused by inherited defects of… Expand
Highly Cited
2004
Highly Cited
2004
Mucopolysaccharidosis type IIIA (SanÐlippo A; McKusick 25290) is caused by a deÐciency of lysosomal sulphamidase activity (EC 3… Expand
2003
2003
Sanfilippo A syndrome, mucopolysaccharidosis type IIIA, is caused by a deficiency of heparan sulphamidase activity, and usually… Expand
1996
1996
Summary4-Methylumbelliferyl-α-d-N-sulphoglucosaminide (MU-α-GlcNS) was synthesized and shown to be a substrate for the lysosomal… Expand
1993
1993
Early amniocentesis performed at 13 weeks gestation was utilized to obtain amniocytes for culture. Sonicates of cultured… Expand
1986
1986
Human sulphamate sulphohydrolase was purified at least 20,000-fold to homogeneity from liver with a three-step four-column… Expand
1981
1981
1. Sulphamidase activity was assayed by incubation of the radiolabelled disaccharide O-(alpha-2-sulphamino-2-deoxy-D… Expand
Highly Cited
1974
Highly Cited
1974
A sulphamidase activity present in rat spleen capable of hydrolysing N-[(35)S]sulphated heparin was studied. This activity was… Expand
1971
1971
Abstract A method for the estimation of arylsulphatases A and B (E.C. 3.1.6.1 arylsulphate sulphohydrolase) in serum is presented… Expand