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Biomarkers are the measurable changes associated with a physiological or pathophysiological process. Unlike blood, urine is not… Expand The endothelium has a central role in the regulation of blood flow through continuous modulation of vascular tone. This is… Expand Aldehyde oxidase-mediated oxidation of N1-methylnicotinamide to N1-methyl-2-pyridine-5-carboxamide (2-PY) and N1-methyl-4… Expand Type 2 diabetes mellitus is the result of a combination of impaired insulin secretion with reduced insulin sensitivity of target… Expand We have isolated a kidney-specific organic cation transporter, rat OCT2, which is distinct from rat OCT1 (Okuda M, Saito H… Expand Abstract The aldehyde oxidases from rabbit and hog livers have been purified to homogeneity by modifications of and additions to… Expand The uptake of N'-methylnicotinamide (NMN) by renal slices of the dog has been studied. NMN is concentrated in renal slices and… Expand In the course of experiments designed to elucidate the structure of reduced diphosphopyridine nucleotide (DPNH) (12), it became… Expand N'-Methylnicotinamide has been shown to be one of the principal excretion products derived from the metabolism ofnicotinic acid… Expand