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The development of transition metal-catalyzed oxidative C-H/C-H cross-coupling between two (hetero)arenes to forge aryl… Expand A sensitive, selective and generic method has been developed for the simultaneous determination of the contents (μgkg(-1) range… Expand The human CYP2A subfamily comprises three genes, CYP2A6, CYP2A7, and CYP2A13. CYP2A6 is active toward many carcinogens and is the… Expand A Salmonella typhimurium tester strain YG7108 2E1/OR co-expressing human CYP2E1 together with human NADPH-cytochrome P450… Expand The demethylation of carcinogenic N-nitrosodimethylamine (NDMA) and N-nitrosomethylaniline (NMA) is catalyzed by horseradish… Expand SummaryRat liver microsomes which were induced either with ethanol or PB were incubated with NDMA or NMA. Formaldehyde generation… Expand The metabolic activation of the esophageal carcinogen methylphenylnitrosamine (MPhN) via alpha-hydroxylation to… Expand The steady state kinetics and isotope effects were examined for demethylation of dimethylnitrosamine and phenylmethylnitrosamine… Expand A microsome-mediated mutagenesis system has been established with the V79 Chinese hamster cell line. The cells, grown in… Expand Summary The mutagenicity of dimethyl, diethyl, di- n -propyl, di- n -butyl, methyl- n -butyl, morpholine, piperidine… Expand