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N(epsilon)-(malondialdehyde)lysine

Known as: MDA-Lys, MDAL, Malondialdehyde-Lysine 
A lysine modification found in proteins resulting from a malondialdehyde attachment to the protein lysine residue. This advanced glycation end… 
National Institutes of Health

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Broader (1)

Lysine
analogs & derivatives

Papers overview

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Highly Cited
2010
Highly Cited
2010
Modifying Apolipoprotein A-I by Malondialdehyde, but Not by an Array of Other Reactive Carbonyls, Blocks Cholesterol Efflux by the ABCA1 Pathway*
Dysfunctional high density lipoprotein (HDL) is implicated in the pathogenesis of cardiovascular disease, but the underlying… 
Highly Cited
2005
Highly Cited
2005
Protein and lipid oxidative damage and complex I content are lower in the brain of budgerigar and canaries than in mice. Relation to aging rate
What are the mechanisms determining the rate of animal aging? Of the two major classes of endothermic animals, bird species are… 
Highly Cited
2000
Highly Cited
2000
Pyridoxamine, an Inhibitor of Advanced Glycation Reactions, Also Inhibits Advanced Lipoxidation Reactions
Maillard or browning reactions lead to formation of advanced glycation end products (AGEs) on protein and contribute to the… 
Highly Cited
2000
Highly Cited
2000
In vivo uptake of radiolabeled MDA2, an oxidation-specific monoclonal antibody, provides an accurate measure of atherosclerotic lesions rich in oxidized LDL and is highly sensitive to their…
To determine whether labeled antibodies against oxidized LDL (OxLDL) offer advantages for quantifying atherosclerosis, we… 
Highly Cited
2000
Highly Cited
2000
Low fatty acid unsaturation: a mechanism for lowered lipoperoxidative modification of tissue proteins in mammalian species with long life spans.
Carbonyl compounds generated by the nonenzymatic oxidation of polyunsaturated fatty acids react with nucleophilic groups in… 
Highly Cited
1999
Highly Cited
1999
Immunohistochemical evidence for an increased oxidative stress and carbonyl modification of proteins in diabetic glomerular lesions.
Advanced glycation end products (AGE) include a variety of protein adducts whose accumulation has been implicated in tissue… 
Review
1999
Review
1999
Carbonyl stress in the pathogenesis of diabetic nephropathy.
Diabetic nephropathy is a major chronic complication of diabetes mellitus and an important cause of increased morbidity and… 
Highly Cited
1999
Highly Cited
1999
A low degree of fatty acid unsaturation leads to lower lipid peroxidation and lipoxidation-derived protein modification in heart mitochondria of the longevous pigeon than in the short-lived rat
Highly Cited
1981
Highly Cited
1981
Essential virulence determinants of different Yersinia species are carried on a common plasmid.
Highly Cited
1974
Highly Cited
1974
Comparison of the Deoxyribonucleic Acid Molecular Weights and Homologies of Plasmids Conferring Linked Resistance to Streptomycin and Sulfonamides
Bacterial strains showing linked resistance to streptomycin (Sm) and sulfonamides (Su) were chosen representing a wide taxonomic… 
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