Semantic Scholar uses AI to extract papers important to this topic.
Interference with the biosynthetic pathway to melanin may be a useful means for developing new chemotherapeutic drugs to combat… Expand SummaryThe rationale for melanoma-specific antitumor agents containing phenolic amines is based in part on the ability of the… Expand N-Acetyl-4-S-cysteaminylphenol 1 is an analogue of a biosynthetic intermediate in the pathway to melanin. It is probably oxidized… Expand N-Acetyl-4-S-cysteaminylphenol (1) has been shown by Jimbow and co-workers to possess useful antimelanoma activity. It is an… Expand Tyrosinase has been suggested as a prodrug-converting enzyme for the treatment of melanoma. We hypothesized that tyrosinase… Expand Chemotherapy of malignant melanoma is still a great challenge, as no effective drugs are available. The development of… Expand This study examined the effect of glutathione on the in vivo depigmenting potency of N-acetyl-4-S-cysteaminylphenol (N-acetyl-4-S… Expand In order to develop a new chemotherapeutic agent based on exploitation of the specific metabolic pathway of malignant melanoma, a… Expand BACKGROUND AND DESIGN
--Melasma is a difficult medical problem to treat. Hydroquinone is administered to many patients, but it is… Expand Summary Previous in vivo studies have shown that 4‐S‐cysteaminylphenol (4‐S‐CAP) and N‐acetly‐4‐S‐ cysteaminylphenol (N‐Ac‐4‐S… Expand