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N 0840

Known as: N-0840 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2006
0119932006

Related topics

Related topics

1 relation

Broader (1)

N(6)-cyclopentyl-9-methyladenine

Related mentions per year

Related mentions per year

1993-2006
19901995200020052010
N 0840
N(6)-cyclopentyl-9-methyladenine

Papers overview

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2006
2006
Role of the second transmembrane domain of rat adenosine A1 receptor in ligand-receptor interaction.
Initial mutagenesis studies exploring the ligand recognition model of A1 adenosine receptor (A1R) mainly focused on the residues… (More)
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2004
2004
Synthesis and biological evaluation of disubstituted N6-cyclopentyladenine analogues: the search for a neutral antagonist with high affinity for the adenosine A1 receptor.
Novel 3,8- and 8,9-disubstituted N(6)-cyclopentyladenine derivatives were synthesised in moderate overall yield from 6… (More)
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2003
2003
An optimized approach to study endocannabinoid signaling: evidence against constitutive activity of rat brain adenosine A1 and cannabinoid CB1 receptors.
At nanomolar concentrations, SR141716 and AM251 act as specific and selective antagonists of the cannabinoid CB1 receptor. In the… (More)
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2002
2002
Synthesis and evaluation of no-carrier-added 8-cyclopentyl-3-(3-[(18)F]fluoropropyl)-1-propylxanthine ([(18)F]CPFPX): a potent and selective A(1)-adenosine receptor antagonist for in vivo imaging.
This report describes the precursor synthesis and the no-carrier-added (nca) radiosynthesis of the new A(1) adenosine receptor (A… (More)
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1999
1999
Role of adenosine A(1) receptors in modulating extracellular adenosine levels.
The purpose of this investigation was to test the hypothesis that A(1) receptors modulate extracellular levels of adenosine in… (More)
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1998
1998
Inverse agonists and neutral antagonists of recombinant human A1 adenosine receptors stably expressed in Chinese hamster ovary cells.
Receptor antagonists can be classified as neutral antagonists or antagonists with inverse agonist activity based on their… (More)
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1993
1993
In vitro and in vivo pharmacological characterization of N6-cyclopentyl-9-methyladenine (N-0840): a selective, orally active A1 adenosine receptor antagonist.
The pharmacological and biochemical profile of N6-cyclopentyl-9-methyladenine (N-0840) was elucidated in vitro and in vivo. In… (More)
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