N-(2-propylpentanoyl)urea

Known as: VPU compound, valproyl urea 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1988-2018
0204019882018

Papers overview

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Review
2015
Review
2015
Critical cell surface immunoreceptors downregulated during HIV infection have previously been identified using non-systematic… (More)
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Highly Cited
2009
Highly Cited
2009
The expression of many putative antiviral genes is upregulated when cells encounter type I interferon (IFN), but the actual… (More)
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Highly Cited
2009
Highly Cited
2009
Tetherin, also known as BST2, CD317 or HM1.24, was recently identified as an interferon-inducible host-cell factor that… (More)
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Highly Cited
2009
Highly Cited
2009
Vpu proteins of pandemic HIV-1 M strains degrade the viral receptor CD4 and antagonize human tetherin to promote viral release… (More)
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Highly Cited
2009
Highly Cited
2009
The primary roles attributed to the human immunodeficiency virus type 1 (HIV-1) Vpu protein are the degradation of the viral… (More)
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Highly Cited
2008
Highly Cited
2008
Human cells possess an antiviral activity that inhibits the release of retrovirus particles, and other enveloped virus particles… (More)
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Highly Cited
2008
Highly Cited
2008
The HIV-1 accessory protein Vpu counteracts a host factor that restricts virion release from infected cells. Here we show that… (More)
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Highly Cited
1998
Highly Cited
1998
HIV-1 Vpu interacts with CD4 in the endoplasmic reticulum and triggers CD4 degradation, presumably by proteasomes. Human beta… (More)
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Highly Cited
1992
Highly Cited
1992
CD4 is an integral membrane glycoprotein which is known as the human immunodeficiency virus (HIV) receptor for infection of human… (More)
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Highly Cited
1990
Highly Cited
1990
A deletion mutation affecting vpu was introduced into an infectious molecular clone of human immunodeficiency virus type 1, and… (More)
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