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N,N-dimethylarginine

Known as: N(G1),N(G1)-dimethylarginine, N(G)-dimethylarginine, N(5)-((dimethylamino)iminomethyl)-L-ornithine 
A methylated derivative of L-arginine that is a competitive inhibitor of nitric oxide synthase (NOS). Asymmetric dimethylarginine (ADMA) is formed… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Reactive oxygen species (ROS) are reactive intermediates of molecular oxygen that act as important second messengers within the… Expand
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Review
2018
Review
2018
In this narrative review, the biological/biochemical impact (toxicity) of a large array of known individual uremic retention… Expand
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Review
2017
Review
2017
In its early stages, symptoms of chronic kidney disease (CKD) are usually not apparent. Significant reduction of the kidney… Expand
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Review
2016
Review
2016
Mammalian arginine metabolism is complex due to the expression of multiple enzymes that utilize arginine as substrate and to… Expand
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Review
2016
Review
2016
Background A growing number of studies linked elevated concentrations of circulating asymmetric (ADMA) and symmetric (SDMA… Expand
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Review
2005
Review
2005
Received June 28, 2004; revision received August 26, 2004; accepted October 15, 2004. The original description of the metabolic… Expand
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Highly Cited
2002
Highly Cited
2002
BACKGROUND An endogenous inhibitor of nitric oxide synthase, asymmetric dimethylarginine (ADMA), is elevated in patients with… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Hyperhomocysteinemia is a putative risk factor for cardiovascular disease, which also impairs endothelium-dependent… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase (NOS). Plasma levels of ADMA… Expand
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Asymmetric dimethylarginine (ADMA) is an endogenous competitive inhibitor of nitric oxide (NO) synthase. Because… Expand
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